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THE EFFECT OF VARIOUS DOSES OF OESTRADIOL 17- ON GLYCOGEN DEPOSITION IN THE RAT UTERUS, CERVIX AND VAGINA

1967; Bioscientifica; Volume: 14; Issue: 2 Linguagem: Inglês

10.1530/jrf.0.0140231

1741-7899

A.T. Gregoire, Haley E. Ramsey, A. Elizabeth Adams,

Effects and risks of endocrine disrupting chemicals

Administration of oestradiol benzoate, 5 to 200 \ g=m\ g, intra- muscularly daily for 3 days, results in glycogen deposition in the uterus and cervix of castrated Wistar rats.The relation between dose of oestro- gen and amount of glycogen deposited is not, however, linear nor did all portions of the tract respond in a similar manner.The glycogen level of the vagina was not affected by the hormone administration, while proges- terone lowered the glycogen content of all portions of the tract.The glycogen metabolism of the mammalian female genital tract is briefly reviewed and discussed.