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Studies on forskolin ring C forming reactions

1994; Elsevier BV; Volume: 50; Issue: 1 Linguagem: Inglês

10.1016/s0040-4020(01)80741-9

1464-5416

Guido Jordine, Stefan Bick, Uwe Möller, Peter Welzel, Birgit Daucher, Gerhard Maas,

Natural product bioactivities and synthesis

Labdane derivative 27 has been prepared from (E,E)-farnesol (4). Selenium- and mercury-mediated cyclization of 24 leads to compounds with the opposite configuration at C-8 as found in forskolin.