Solitary Langerhans Cell Histiocytoma: An Unusual Form of Hashimoto‐Pritzker Histiocytosis?
1990; Wiley; Volume: 7; Issue: 4 Linguagem: Inglês
10.1111/j.1525-1470.1990.tb01030.x
ISSN1525-1470
AutoresIsabelle Masouyé, Pierre Chavaz, Oscar Daniel Salomón, J. Balderer, Pierre Carraux, J.‐H. Saurat,
Tópico(s)RNA regulation and disease
ResumoAbstract: A 2‐month‐old girt acutely developed a brownish, firm nodule on the left thigh. The lesion was surgically removed when the patient was age 3 months, and histology showed a massive dermal infiltration by large histiocytic cells with abundant ground glass cytoplasm. Most cells were S100 protein positive. Electron microscopic examination revealed the presence of Birbeck granules in about 30% of the histiocytes, as well as laminated dense bodies and wormlike bodies. No recurrence was observed during follow‐up for three years. We believe that this case, like the one previously reported, represents a clinical variant of Hashimoto‐Pritzker disease.
Referência(s)