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Viral mechanisms of immune evasion

2000; Elsevier BV; Volume: 21; Issue: 9 Linguagem: Inglês

10.1016/s0167-5699(00)01699-6

1355-8242

Antonio Alcamı́, Ulrich H. Koszinowski,

Herpesvirus Infections and Treatments

During the millions of years they have coexisted with their hosts, viruses have learned how to manipulate host immune control mechanisms. Viral gene functions provide an overview of many relevant principles in cell biology and immunology. Our knowledge of viral gene functions must be integrated into virus–host interaction networks to understand viral pathogenesis, and could lead to new anti-viral strategies and the ability to exploit viral functions as tools in medicine.