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Alu elements: know the SINEs

2011; Springer Science+Business Media; Volume: 12; Issue: 12 Linguagem: Inglês

10.1186/gb-2011-12-12-236

1465-6914

Prescott L. Deininger,

RNA Research and Splicing

Alu elements are primate-specific repeats and comprise 11% of the human genome. They have wide-ranging influences on gene expression. Their contribution to genome evolution, gene regulation and disease is reviewed.