UNTOWARD REACTIONS FOLLOWING TOXIN TREATMENT FOR DERMATITIS VENENATA

1929; American Medical Association; Volume: 20; Issue: 1 Linguagem: Inglês

10.1001/archderm.1929.01440010091011

ISSN

1538-3652

Autores

H. J. Templeton,

Tópico(s)

Chemotherapy-related skin toxicity

Resumo

In 1916, Schamberg 1 informally reported favorable results following treatment for dermatitis venenata due to ivy ( Rhus toxicodendron ) by means of oral administration of an alcoholic extract of the leaves of the plant. He made a formal report 2 in 1919, in which he advised two types of treatment: preseasonal prophylactic and seasonal curative. In both treatments, he began with the administration of very small doses (1 or 2 drops) of the alcoholic extract by mouth. In the preseasonal cases the extract was given three times daily, each dose being increased by 1 drop until 21 drops were reached, at which time the dosage was increased to 1 teaspoonful. This dosage was to be continued throughout the season. If dermatitis had already developed, the system of treatment was the same, except that each dose was increased by 2 drops. After the dosage reached 18 drops, it was increased to 1

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