Artigo Acesso aberto Revisado por pares

Epigastric impedance: a non-invasive method for the assessment of gastric emptying and motility.

1985; BMJ; Volume: 26; Issue: 6 Linguagem: Inglês

10.1136/gut.26.6.607

ISSN

1468-3288

Autores

G. R. McClelland, J. A. Sutton,

Tópico(s)

Gastrointestinal motility and disorders

Resumo

Objective: To study the association of cannabis use on in-hospital outcomes in patients with cancer related pain. Background: Cancer related pain is a serious health concern with data suggesting more than 50% of oncology patients suffer from cancer related pain. As the use of cannabis is legalized and increasing in many areas of USA, it is important to understand the effect of cannabis use on in-hospital outcomes in this patient population as compared to non-cannabis users. Design/Methods: The Nationwide Inpatient Sample (NIS) was reviewed from 2007 to 2014 to identify patients with cancer related pain using the ICD CM code for neoplasm related pain, and appropriate codes for cannabis abuse. Trends were analyzed using the Cochrane-Armitage test. Differences between categorical variables were tested using the chi-square test and continuous variables were analyzed using the Student t-test. Predictors to assess the association between cannabis abuse and in hospital mortality were analyzed using a multivariable logistic regression model. Results: We identified 682,933 patients in our study period with hospitalization due cancer related pain, of which 4,254 had a history of cannabis abuse. During this period, we observed a rising trend in cannabis abuse in this patient population from 116 to 1185. The cannabis-cancer pain group was associated with lower in hospital mortality (4.7% vs 9.0%; p <0.0001), higher median cost of hospitalization ($16,665 vs $14,595) and higher incidence of discharge against medical advice (1.8% vs 0.4%, p <0.0001). However, length of stay was similar among the two groups (7.0 vs 6.9 days, p = 0.74). Conclusions: Based on this data, cannabis use is associated with decreased in-hospital mortality and is not associated with any difference in duration of hospitalization. This data elucidates an increasingly important area of study to determine the effects of cannabis use in cancer related pain. Disclosure: Dr. Myers has nothing to disclose. Dr. Savani has nothing to disclose. Dr. Kumar has nothing to disclose. Dr. Brock has nothing to disclose.

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