Cigarette Smoking, Alcohol Consumption, and Risk of ARDS
2000; Elsevier BV; Volume: 117; Issue: 1 Linguagem: Inglês
10.1378/chest.117.1.163
ISSN1931-3543
AutoresCarlos Iribarren, David R. Jacobs, Stephen Sidney, Myron D. Gross, Mark D. Eisner,
Tópico(s)Climate Change and Health Impacts
ResumoTo examine the association of cigarette smoking and alcohol consumption with hospital presentation of ARDS in a well-defined, multiethnic population.Retrospective cohort study.Health maintenance organization in Northern California.A total of 121,012 health plan subscribers (54.2% women), aged 25 to 89 years.Hospital presentation of ARDS (validated by medical chart review) from baseline in 1979 to 1985 through the end of 1993 (median, 9.9 years).There were 56 cases of ARDS (33 in men, 23 in women). The case fatality rate was 39% in both genders. ARDS was independently related to increasing age (rate ratio of 10 years, 1.38; 95% confidence interval [CI], 1.12 to 1.71), to current smoking of < 20 cigarettes/d (rate ratio vs never cigarette smokers, 2.85; 95% CI, 1. 23 to 6.60), and to current cigarette smoking of > or = 20 cigarettes/d (rate ratio vs never smokers, 4.59; 95% CI, 2.13 to 9.88). No association was observed between alcohol consumption and ARDS.The results of this study suggest a relationship (with evidence of dose-response effect) between cigarette smoking and ARDS. Assuming a causal relationship, approximately 50% of ARDS cases were attributable to cigarette smoking.
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