Des-tyrosine-γ-endorphin: H-reflex response similar to neuroleptics
1981; Elsevier BV; Volume: 28; Issue: 18 Linguagem: Inglês
10.1016/0024-3205(81)90647-0
ISSN1879-0631
AutoresJohn Metz, Daniel A. Busch, Herbert Y. Meltzer,
Tópico(s)Receptor Mechanisms and Signaling
ResumoAbstract In a study of eight schizophrenic patients, des-tyrosine-γ-endorphin was found to significantly reduce secondary facilitation of the H-reflex recovery curve. This result is similar to the effect found after treatment with classical neuroleptic medication. The effect is different from that produced by lithium carbonate or anti-depressants. This suggests that des-tyrosine-γ-endorphin and neuroleptics have a similar pharmacological action in man.
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