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Interpretations of Fundus Autofluorescence from Studies of the Bisretinoids of the Retina

2010; Cadmus Press; Volume: 51; Issue: 9 Linguagem: Inglês

10.1167/iovs.10-5852

1552-5783

Janet R. Sparrow, Kee Dong Yoon, Yalin Wu, Kazunori Yamamoto,

Retinoids in leukemia and cellular processes

Elevated fundus autofluorescence signals can reflect enhanced lipofuscin in RPE cells, augmented fluorescence due to photooxidation, and/or excess bisretinoid fluorophores in photoreceptor cells due to mishandling of vitamin A aldehyde by dysfunctional cells.