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Cataracts induced by surface active agents

1974; Elsevier BV; Volume: 19; Issue: 1 Linguagem: Inglês

10.1016/0014-4835(74)90069-4

1096-0007

Donald R. Sanders, Edward Cotlier, George J. Wyhinny, Leonard Millman,

Intraocular Surgery and Lenses

Intravitreally-administered anionic, cationic and neutral surface active agents are all capable of producing cataracts. The developing cataracts are characterized by increased hydration, loss of dry weight, progressive increases in Na+ concentration, and progressive decreases in K+ concentration. Glycolytic metabolism is only moderately decreased in the advanced stages of cataract. Surface active membrane damage is discussed in reference to the pathogenesis of cataract.