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Tauroacidins A and B, new bromopyrrole alkaloids possessing a taurine residue from Hymeniacidon sponge

1997; Elsevier BV; Volume: 53; Issue: 49 Linguagem: Inglês

10.1016/s0040-4020(97)10097-7

1464-5416

Jun’ichi Kobayashi, Kenjiro Inaba, Masashi Tsuda,

Synthesis and Reactions of Organic Compounds

Two new bromopyrrole alkaloids, tauroacidins A (1) and B (2), with tyrosine kinase inhibitory activity have been isolated from an Okinawan marine sponge Hymeniacidon sp. and the structures were elucidated on the basis of spectral data and chemical means. Tauroacidins A (1) and B (2) are rare bromopyrrole alkaloids possessing a taurine residue.