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Woofer-tweeter adaptive optics scanning laser ophthalmoscopic imaging based on Lagrange-multiplier damped least-squares algorithm

2011; Optica Publishing Group; Volume: 2; Issue: 7 Linguagem: Inglês

10.1364/boe.2.001986

2156-7085

Weiyao Zou, Xiaofeng Qi, Stephen A. Burns,

Glaucoma and retinal disorders

We implemented a Lagrange-multiplier (LM)-based damped least-squares (DLS) control algorithm in a woofer-tweeter dual deformablemirror (DM) adaptive optics scanning laser ophthalmoscope (AOSLO).The algorithm uses data from a single Shack-Hartmann wavefront sensor to simultaneously correct large-amplitude low-order aberrations by a woofer DM and small-amplitude higher-order aberrations by a tweeter DM.We measured the in vivo performance of high resolution retinal imaging with the dual DM AOSLO.We compared the simultaneous LM-based DLS dual DM controller with both single DM controller, and a successive dual DM controller.We evaluated performance using both wavefront (RMS) and image quality metrics including brightness and power spectrum.The simultaneous LM-based dual DM AO can consistently provide near diffraction-limited in vivo routine imaging of human retina.