Evidence of disturbed meiosis in a man referred for intracytoplasmic sperm injection
1998; Elsevier BV; Volume: 351; Issue: 9107 Linguagem: Inglês
10.1016/s0140-6736(05)60611-3
ISSN1474-547X
AutoresMHEC Pieters, RM Speed, P. de Boer, J. T. M. Vreeburg, G. Dohle, PA in't Veld,
Tópico(s)Reproductive Health and Technologies
ResumoIntracytoplasmic sperm injection (ICSI) has become the treatment of choice in male infertility due to extreme oligozoospermia. Initially, the technique was limited to the selection and injection of motile spermatozoa with normal morphology; although it has now been shown that spermatozoa with abnormal morphology can also be used successfully. 1 Tasdemir I Tasdemir M Tavukcuoglu S Kahraman S Biberoglu K Effect of abnormal sperm head morphology on the outcome of intracytoplasmic sperm injection in humans. Human Reproduction. 1997; 12: 1214-1217 Crossref PubMed Scopus (70) Google Scholar We describe a patient referred for ICSI who presented with phenotypically abnormal sperm and we show that in this patient the disturbed spermatogenesis was associated with chromosome abnormalities and abnormal meiosis.
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