Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients
1987; Elsevier BV; Volume: 1; Issue: 3 Linguagem: Inglês
10.1016/0920-1211(87)90043-x
ISSN1872-6844
AutoresC Loeb, E Benassi, Gian‐Paolo Bo, Leonardo Cocito, Maura Maffini, Pierangelo Scotto,
Tópico(s)Epilepsy research and treatment
ResumoThe effect of the combined administration of gamma-aminobutyric acid (GABA) and phosphatidylserine was evaluated in a pilot study of 42 patients with drug-resistant epilepsy. The group included patients with complex partial seizures, simple partial seizures and absence seizures. Patients with complex partial seizures and simple partial seizures showed no significant improvement; on the other hand, there was a remarkable decrease in absence seizures, linearly related to the dose of GABA and phosphatidylserine. Side effects occurred in 9 patients and were usually mild.
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