Technetium-99m macroaggregated albumin: A new lung scanning agent

1967; Pergamon Press; Volume: 18; Issue: 3 Linguagem: Inglês

10.1016/0020-708x(67)90101-9

ISSN

1878-1284

Autores

Carl C. Peterson, Frederick J. Bonte,

Tópico(s)

Radiation Therapy and Dosimetry

Resumo

Preliminary studies using macroaggregated human serum albumin tagged with technetium-99m for lung scanning in rabbits are very encouraging. No problems were encountered in the preparation of the Tc99m tagged macroaggregates, and, as might be predicted, the administration of the prepared macroaggregate suspension results in very selective localization of activity in the lungs and high counting rates. Because of the extremely favorable 6 hr half-life and low photon energy of this isotope, large doses may be used to provide a counting rate which will facilitate rapid scanning, while reducing total patient radiation exposure. For these reasons it appears that MAA tagged with Tc99m may be the preferred agent for lung scanning.

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