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A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

2011; Elsevier BV; Volume: 88; Issue: 6 Linguagem: Inglês

10.1016/j.ajhg.2011.05.003

1537-6605

Maria Teresa Landi, Nilanjan Chatterjee, Kai Yu, Lynn R. Goldin, Alisa M. Goldstein, Melissa Rotunno, Kari G. Rabe, Kevin B. Jacobs, William Wheeler, Meredith Yeager, Andrew W. Bergen, Qizhai Li, Dario Consonni, Angela Cecilia Pesatori, Sholom Wacholder, Michael J. Thun, W. Ryan Diver, Martin M. Oken, Jarmo Virtamo, Demetrius Albanes, Zhaoming Wang, Laurie Burdette, Kimberly F. Doheny, Elizabeth Pugh, Cathy C. Laurie, Paul Brennan, Rayjean J. Hung, Valérie Gaborieau, James D. McKay, Mark Lathrop, John McLaughlin, Ying Wang, Ming‐Sound Tsao, Margaret R. Spitz, Yufei Wang, Hans E. Krokan, Lars J. Vatten, Frank Skorpen, Egil Arnesen, Simone Benhamou, Christine Bouchard, Andres Metspalu, Tõnu Vooder, Mari Nelis, Kristjan Välk, John K. Field, Chu Chen, Gary Goodman, Patrick Sulem, Guðmar Þorleifsson, Thorunn Rafnar, Timothy Eisen, Wiebke Sauter, Albert Rosenberger, Heike Bickeböller, Angela Risch, Jenny Chang-Claude, H. Erich Wichmann, Hreinn Stefánsson, Richard S. Houlston, Christopher I. Amos, Joseph F. Fraumeni, Sharon A. Savage, Pier Alberto Bertazzi, Margaret A. Tucker, Stephen Chanock, Neil E. Caporaso,

Epigenetics and DNA Methylation

(The American Journal of Human Genetics 85, 679–691; November 13, 2009) In the original version of this paper, Andres Metspalu's name was misspelled. Above is the corrected author list. The authors regret this error. A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for AdenocarcinomaLandi et al.The American Journal of Human GeneticsOctober 15, 2009In BriefThree genetic loci for lung cancer risk have been identified by genome-wide association studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not well established. We conducted a GWAS of lung cancer and its major histologic types, genotyping 515,922 single-nucleotide polymorphisms (SNPs) in 5739 lung cancer cases and 5848 controls from one population-based case-control study and three cohort studies. Results were combined with summary data from ten additional studies, for a total of 13,300 cases and 19,666 controls of European descent. Full-Text PDF Open Archive