Pathological effects and radioautographic localization of i131 in humans. Postmortem study in nine patients
1951; Wiley; Volume: 4; Issue: 5 Linguagem: Inglês
10.1002/1097-0142(195109)4
ISSN1097-0142
AutoresJohn T. Godwin, Benedict J. Duffy, Patrick Fitzgerald, J. B. Trunnell, Rulon W. Rawson,
Tópico(s)Cancer Immunotherapy and Biomarkers
ResumoCancerVolume 4, Issue 5 p. 936-951 ArticleFree Access Pathological effects and radioautographic localization of i131 in humans. Postmortem study in nine patients John T. Godwin M.D., John T. Godwin M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New York Special Fellow, American Cancer Society, Inc., at the Department of Pathology, Memorial Center for Cancer and Allied Diseases, and the Department of Physics, Sloan-Kettering Institute, New York, New YorkSearch for more papers by this authorB. J. Duffy Jr. M.D., B. J. Duffy Jr. M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New York Damon Runyon Clinical Research FellowSearch for more papers by this authorPatrick J. Fitzgerald M.D., Patrick J. Fitzgerald M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New YorkSearch for more papers by this authorJ. B. Trunnell M.D., J. B. Trunnell M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New York Damon Runyon Clinical Research FellowSearch for more papers by this authorRulon W. Rawson M.D., Rulon W. Rawson M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New YorkSearch for more papers by this author John T. Godwin M.D., John T. Godwin M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New York Special Fellow, American Cancer Society, Inc., at the Department of Pathology, Memorial Center for Cancer and Allied Diseases, and the Department of Physics, Sloan-Kettering Institute, New York, New YorkSearch for more papers by this authorB. J. Duffy Jr. M.D., B. J. Duffy Jr. M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New York Damon Runyon Clinical Research FellowSearch for more papers by this authorPatrick J. Fitzgerald M.D., Patrick J. Fitzgerald M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New YorkSearch for more papers by this authorJ. B. Trunnell M.D., J. B. Trunnell M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New York Damon Runyon Clinical Research FellowSearch for more papers by this authorRulon W. Rawson M.D., Rulon W. Rawson M.D. Pathological Laboratories, and the Departments of Physics and Clinical Investigation, Memorial Center for Cancer and Allied Diseases, New York, New YorkSearch for more papers by this author First published: September 1951 https://doi.org/10.1002/1097-0142(195109)4:5 3.0.CO;2-XCitations: 7 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 W. Bloom, Ed.: Histopathology of Irradiation from External and Internal Sources. New York. McGraw-Hill Book Co., Inc., 1918. 2 Dobyns, B. M., and Lennon, B: A study of the histopathology and physiologic function of thyroid tumors, using radioactive iodine and radioautography. J. Clin. Endocrinol. 8: 732– 748, 1948. 3 Duffy, B. J. Jr., and Godwin, J. T.: The effects of I131 on thyroid and ovarian function in rats. Unpublished data. 4 Duffy, C. F.: Effects of radiation on normal tissues. III. Effects of radiation on the blood and the hemopoietic tissues, including the spleen, the thymus and the lymph nodes Arch. Path. 34: 562– 608, 1942. 5 Dunlap, C. E.: Effects of radiation. In W. A. D. Anderson, Ed.: Pathology. St. Louis, C. V. Mosby Co. 1948; pp. 175– 195. 6 Endicott, K. M., and Yagoda, H: Microscopic historadiographic technic for locating and quantitating radioactive elements in tissues. Proc. Soc. Exper. Biol. & Med. 64: 170– 172, 1947. 7 Evans, T. C.: Radioautographs in which tissue is mounted directly on photographic plate. Proc. Soc. Exper. Biol. & Med. 64: 313– 315. 1947. 8 Evans, T. C.: Radioautographs: methods and uses. In Radiology. Brookhaven Conference Report BNL-C-5. Brookhaven National Laboratory, Associated Universities, Inc. Upton, N. Y. 1948: pp. 95– 98. 9 Fitzgerald, P. J.: Histologic types of thyroid carcinoma and their respective abilities to store radioactive iodine131 as demonstrated by radioautograms. In Radiology. Brookhaven Conference Report BNL-C-5. Brookhaven National Laboratory, Associated Universities. Inc. Upton, N. Y. 1948; pp. 91– 94. 10 Fitzgerald, P. J., and Foote, F. W. Jr: The function of various types of thyroid carcinoma as revealed by the radioautographic demonstration of radioactive iodine (I131). J. Clin. Endocrinol. 9: 1153– 1170, 1949. 11 Fitzgerald, P. J.; Foote, F. W.Jr, and Hill, R. F.: Concentration of I131 in thyroid cancer, shown by radioautography; a study of 100 consecutive cases showing the relation of histological structure to the function of thyroid carcinoma. Cancer 3: 86– 105, 1950. 12 Frantz, V. K.; Quimby, E. H., and Evans, T. C.: Radioactive iodine studies of functional thyroid carcinoma Radiology 51: 532– 552, 1948. 13 Frantz, V. K.; Ball, R. P.; Keston, A. S., and Palmer, W. W.: Thyroid carcinoma with metastases, studied with radioactive iodine Ann. Surg. 119: 668– 689, 1944. 14 Frazell, E. L., and Foote, F. W. Jr: The natural history of thyroid cancer; a review of 301 cases. J. Clin. Endocrinol. 9: 1023– 1030, 1949. 15 Friedman, N. B.: Effects of radiation on normal tissues. IV. Effects of radiation on the gastrointestinal tract, including the salivary glands, the liver and the pancreas Arch. Path. 34: 749– 787, 1942. 16 Gates, O: Effects of radiation on normal tissues. XII. Effects on bone, cartilage and teeth. Arch. Path. 35: 323– 340, 1943. 17 Godwin, J. T.: Unpublished data. 18 Goldberg, R. C., and Chaikoff, I. L.: The cytological changes that occur in the anterior pituitary glands of rats injected with various doses of I131 and their significance in the estimation of thyroid function. Endocrinology 46: 91– 104, 1950. 19 Goldberg, R. C.; Chaikoff, I. L.; Lindsay, S., and Feller, D. D.: Histopathological changes induced in the normal thyroid and other tissues of the rat by internal radiation with various doses of radioactive iodine Endocrinology 46: 72– 90, 1950. 20 Gorbman, A: Tumorous growths in the pituitary and trachea following radiotoxic dosages of I131. Proc. Soc. Exper. Biol. & Med. 71: 237– 240, 1949. 21 Hamilton, J. G.; Soley, M. H., and Eichorn, K. B.: Deposition of radioactive iodine in human thyroid tissue Univ. California Publ., Pharmacol. (no. 28) 1: 339– 367, 1940. 22 Keston, A. S.; Ball, R. P.; Frantz, V. K., and Palmer, W. W.: Storage of radioactive iodine in a metastasis from thyroid carcinoma Science 95: 362– 363, 1942. 23 Kreutzer, F. L.; Miller, E. R.; Soley, M. H., and Lindsay, S: Histologic localization of absorbed radioactive iodine in some human thyroid diseases. Arch. Surg. 60: 707– 720, 1950. 24 Lea, D. E.: Actions of Radiations on Living Cells. London. Cambridge University Press. 1947. 25 Leblond, C. P.: Localization of newly administered iodine in thyroid gland as indicated by radioiodine J. Anat. 77: 149– 152, 1943. 26 Leblond, C. P.; Puppel, I. D.; Riley, E; Radike, M., and Curtis, G. M.: Radioiodine and iodine fractionation studies of human goitrous thyroids J. Biol. Chem. 162: 275– 285, 1946. 27 Liebow, A. A.; Warren, S., and DeCoursey, E: Pathology of atomic bomb casualities. Am. J. Path. 25: 853– 1027, 1949. 28 Marinelli, L. D., and Hill, R. F.: Radioautography; some physical and radiobiological aspects of the technique as applied to thin specimens Am. J. Roentgenol. 59: 396– 403, 1948. 29 Marinelli, L. D.; Foote, F. W.; Hill, R. F., and Hocker, A. F.: Retention of radioactive iodine in thyroid carcinomas; histopathologic and radio-autographic studies Am. J. Roentgenol. 58: 17– 32, 1947. 30 Puppel, I. D.; Leblond, C. P., and Curtis, G. M.: The surgical therapeutic significance of the functional behavior of thyroid nodules Ann. Surg. 125: 257– 281, 1947. 31 Rall, J. E.; Keating, F. R.Jr.; Power, M. H., and Bennett, W. A.: The distribution of radioiodine in a patient with metastatic adenocarcinoma of the thyroid; report of a case J. Clin. Endocrinol. 9: 1379– 1391, 1949. 32 Rawson, R. W.; Marinelli, L. D.; Skanse, B. N.; Trunnell, J., and Fluharty, R. G.: The effect of total thyroidectomy on the function of metastatic thyroid cancer J. Clin. Endocrinol. 8: 826– 841, 1948. 33 Salter, W. T.: The Endocrine Function of Iodine. Cambridge. Harvard University Press. 1940. 34 Seidlin, S. M.; Marinelli, L. D., and Oshry, E: Radioactive iodine therapy; effect on functioning metastases of adenocarcinoma of the thyroid. J. A. M. A. 132: 838– 847, 1946. 35 Seidlin, S. M.; Oshry, E., and Yalow, A. A.: Spontaneous and experimentally induced uptake of radioactive iodine in metastases from thyroid carcinoma: a preliminary report J. Clin. Endocrinol. 8: 423– 432, 1948. 36 Seidlin, S. M.; Rossman, I; Oshry, E., and Siegel, E: Radioiodine therapy of metastases from carcinoma of the thyroid: a six-year progress report. J. Clin. Endocrinol. 9: 1122– 1137, 1949. 37 Simmel, E. B.; Fitzgerald, P. J., and Godwin, J. T.: Staining of radioautographs with metanil yellow and iron hematoxylin Stain Technol. 26: 25– 28, 1951. 38 Stewart, F. W.: Radiosensitivity of tumors Arch. Surg. 27: 979– 1064, 1933. 39 Trunnell, J. B.; Rawson, R. W.; Marinelli, L. D., and Hill, R.: The effect of thyroid stimulating hormone on the function of human normal and malignant thyroid tissue. [Abstr.] J. Clin. Endocrinol. 8: 598, 1948. 40 Trunnell, J. B.; Duffy, B. J.Jr.; Godwin, J. T.; Peacock, W; Kirschner, L., and Hill, R: The distribution of radioactive iodine in human tissues: necropsy study in nine patients. J. Clin. Endocrinol. 10: 1007– 1021, 1950. 41 Trunnell, J. B.; Marinelli, L. D.; Duffy, B. J.Jr.; Hill, R.; Peacock, W., and Rawson, R. W.: The treatment of metastatic thyroid cancer with radioactive iodine; credits and debits J. Clin. Endocrinol. 9: 1138– 1152, 1949. 42 Warren, S: Effects of radiation on normal tissues. I. Introduction. II. The effects of radiation on the cell. V. Effects on the respiratory system. VI. Effects of radiation on the cardiovascular system. VII. Effects of radiation on the urinary system. VIII. Effects on the gonads. IX. Effects on the nervous system. X. Effects on organs of special sense. XI. Effects on endocrine glands. XIII. Effects on the skin. XIV. Effects on striated muscle. XV. Effects on the germ plasm and the embryo. Arch. Path. 34: 443– 450; 917–931; 1070–1079; 1079–1084, 1942. 35: 121–127; 127–139; 304–313; 313–323; 340–347; 347–349; 349–353, 1913. 43 Wells, H. G.: Chemical Pathology; Being a Discussion of General Pathology from the Standpoint of the Chemical Processes Involved, 4th ed. Philadelphia. W. B. Saunders Co. 1920; pp. 464– 465. Citing Literature Volume4, Issue5September 1951Pages 936-951 ReferencesRelatedInformation
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