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Sustained favorable long-term prognosis of negative stress echocardiography following uncomplicated myocardial infarction

2002; Elsevier BV; Volume: 90; Issue: 2 Linguagem: Inglês

10.1016/s0002-9149(02)02439-6

1879-1913

Riccardo Bigi, Lauro Cortigiani, Pier Romano Mariani, Jeroen J. Bax,

Pericarditis and Cardiac Tamponade

Dobutamine stress echocardiography (DSE) has been increasingly used in the last few years for risk stratification of patients after acute myocardial infarction (AMI) 1 Carlos M.E. Smart S.C. Wynse J.C. Sagar K.B. Dobutamine stress echocardiography for risk stratification following acute myocardial infarction. Circulation. 1997; 95: 1402-1410 Crossref PubMed Scopus (157) Google Scholar , 2 Sicari R. Picano E. Landi P. Pingitore A. Bigi R. Coletta C. Heyman J. Casazza F. Previtali M. Mathias Jr, W. et al. Echo Dobutamine International Cooperative (EDIC) StudyThe prognostic value of dobutamine-atropine stress echocardiography early after acute myocardial infarction. J Am Coll Cardiol. 1997; 29: 254-260 Abstract Full Text Full Text PDF PubMed Scopus (179) Google Scholar , 3 Bigi R. Galati A. Curti G. Coletta C. Partesana N. Bordi L. Barlera S. Ceci V. Occhi G. Fiorentini C. Prognostic value of residual ischemia assessed by means of exercise electrocardiography and dobutamine stress echocardiography after uncomplicated myocardial infarction. Eur Heart J. 1997; 18: 1873-1881 Crossref PubMed Scopus (41) Google Scholar , 4 Picano E. Sicari R. Landi P. Cortigiani L. Bigi R. Coletta C. Galati A. Heyman J. Mattioli R. Previtali M. et al. EDIC (Echo Dobutamine International Cooperative) Study GroupPrognostic value of myocardial viability in medically treated patients with global left ventricular dysfunction early after an acute uncomplicated myocardial infarction A dobutamine stress echocardiographic study. Circulation. 1998; 98: 1078-1084 Crossref PubMed Scopus (166) Google Scholar , 5 Previtali M. Fetiveau R. Lanzarini L. Cavalotti C. Klersy C. Prognostic value of myocardial viability and ischemia detected by dobutamine stress echocardiography early after acute myocardial infarction treated with thrombolysis. J Am Coll Cardiol. 1998; 32: 380-386 Abstract Full Text Full Text PDF PubMed Scopus (52) Google Scholar , 6 Salustri A. Ciavatti M. Seccareccia F. Palamara A. Prediction of cardiac events after uncomplicated acute myocardial infarction by clinical variables and dobutamine stress test. J Am Coll Cardiol. 1999; 34: 435-440 Abstract Full Text Full Text PDF PubMed Scopus (35) Google Scholar and proved to convey incremental prognostic information compared with standard exercise electrocardiography. 7 Bigi R. Galati A. Desideri A. Bax J.J. Coletta C. Fiorentini C. Fioretti P.M. Incremental prognostic value of stress echocardiography as adjunctive test to exercise electrocardiography following uncomplicated myocardial infarction. Heart. 2001; 85: 417-423 Crossref PubMed Scopus (15) Google Scholar In particular, a very high negative predictive value has been reported in patients with uncomplicated AMI. 2 Sicari R. Picano E. Landi P. Pingitore A. Bigi R. Coletta C. Heyman J. Casazza F. Previtali M. Mathias Jr, W. et al. Echo Dobutamine International Cooperative (EDIC) StudyThe prognostic value of dobutamine-atropine stress echocardiography early after acute myocardial infarction. J Am Coll Cardiol. 1997; 29: 254-260 Abstract Full Text Full Text PDF PubMed Scopus (179) Google Scholar , 3 Bigi R. Galati A. Curti G. Coletta C. Partesana N. Bordi L. Barlera S. Ceci V. Occhi G. Fiorentini C. Prognostic value of residual ischemia assessed by means of exercise electrocardiography and dobutamine stress echocardiography after uncomplicated myocardial infarction. Eur Heart J. 1997; 18: 1873-1881 Crossref PubMed Scopus (41) Google Scholar However, most studies have included only short- or medium-term follow-up; therefore, information on long-term negative predictive value is still lacking. The aim of this study was twofold: (1) to verify the duration of the good prognostic implication by a negative DSE after uncomplicated AMI, and (2) to identify possible markers of future cardiac events in this population.