Artigo Revisado por pares

Hydrophobicity in modified water models

2008; Elsevier BV; Volume: 452; Issue: 4-6 Linguagem: Inglês

10.1016/j.cplett.2008.01.005

ISSN

1873-4448

Autores

Giuseppe Graziano,

Tópico(s)

Phase Equilibria and Thermodynamics

Resumo

Molecular level explanation of the poor solubility in water of nonpolar species is still a debated topic. Recently, Lynden-Bell and Head-Gordon [R.M. Lynden-Bell, T. Head-Gordon, Mol. Phys. 104 (2006) 3593] have compared in detail, at room temperature and atmospheric pressure, the hydrophobicity of suitably modified water models with that of the realistic SPC/E water model. It is shown that, by using the effective size of liquid molecules and the experimental density of water, scaled particle theory calculations reproduce satisfactorily the results of Lynden-Bell and Head-Gordon. Hydrophobicity is mainly determined by a trade-off between the effect of the small size of water molecules and the effect of the low value of its volume packing density.

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