Artigo Acesso aberto Revisado por pares

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

2014; Cell Press; Volume: 9; Issue: 4 Linguagem: Inglês

10.1016/j.celrep.2014.10.041

ISSN

2639-1856

Autores

Niamh Mannion, Sam M. Greenwood, Robert S. Young, Sarah L. Cox, James Brindle, David F. Read, Christoffer Nellåker, Cornelia Vesely, Chris P. Ponting, Paul McLaughlin, Michael F. Jantsch, Julia R. Dorin, Ian R. Adams, A.D.J. Scadden, Marie Öhman, Liam P. Keegan, Mary A. O’Connell,

Tópico(s)

interferon and immune responses

Resumo

primarily the interferon-inducible isoformWe propose that inosine helps innate immunity to distinguish cellular from viral RNA

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