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Localization of3H-norepinephrine binding sites in the trout gill

1985; Wiley; Volume: 235; Issue: 2 Linguagem: Inglês

10.1002/jez.1402350218

1097-010X

N. P. Nekvasil, Kenneth R. Olson,

Neuroscience of respiration and sleep

Abstract Tritiated norepinephrine (Nepi) or Epinephrine (Epi) was perfused through isolated gills of rainbow trout ( Salmo gairdneri ) and the affinity of vascular tissues for the amines examined by autoradiography. Pillar cells and certain endothelial cells in the filamental sinus accumulate 3 H‐Nepi extensively. The afferent and efferent filamental arteries and filamental nutrient vessels did not bind 3 H‐Nepi. Pillar cell and venous endothelial accumulation is selective for Nepi; Epi is not accumulated by these cells, and Nepi uptake can be inhibited by imipramine. These results suggest that pillar and venous endothelial cells are involved in regulation of plasma Nepi.