Artigo Revisado por pares

Cytotoxic Polyketides from a Marine-derived Fungus Aspergillus glaucus

2008; American Chemical Society; Volume: 71; Issue: 11 Linguagem: Inglês

10.1021/np800303t

ISSN

1520-6025

Autores

Lin Du, Tianjiao Zhu, Hongbing Liu, Yuchun Fang, Weiming Zhu, Qianqun Gu,

Tópico(s)

Plant-Microbe Interactions and Immunity

Resumo

Eight new aromatic polyketides (2, 4−6, 8, 14, 16, and 17) together with eight known analogues (3, 7, 9−13, and 15) were isolated from the marine-derived fungus Aspergillus glaucus. The structures and stereochemistry of the new compounds were elucidated by spectroscopic and chemical methods, and their cytotoxicities were evaluated against the HL-60 and A-549 cell lines.

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