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Iridic and retinal coloboma associated with prenatal methimazole exposure

2005; Wiley; Volume: 139A; Issue: 2 Linguagem: Inglês

10.1002/ajmg.a.30917

1552-4833

Michihiko Aramaki, Isamu Hokuto, Tadashi Matsumoto, Hitoshi Ishimoto, Makoto Inoue, Takehiro Kimura, Yoichi Oikawa, Kazushige Ikeda, Yasunori Yoshimura, Takao Takahashi, Kenjiro Kosaki,

Genomic variations and chromosomal abnormalities

American Journal of Medical Genetics Part AVolume 139A, Issue 2 p. 156-158 Research Letter Iridic and retinal coloboma associated with prenatal methimazole exposure Michihiko Aramaki, Michihiko Aramaki Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorIsamu Hokuto, Isamu Hokuto Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorTadashi Matsumoto, Tadashi Matsumoto Department of Obstetrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorHitoshi Ishimoto, Hitoshi Ishimoto Department of Obstetrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorMakoto Inoue, Makoto Inoue Department of Ophthalmology, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorTokuhiro Kimura, Tokuhiro Kimura Department of Pathology, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorYo-ichi Oikawa, Yo-ichi Oikawa Department of Internal Medicine, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorKazushige Ikeda, Kazushige Ikeda Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorYasunori Yoshimura, Yasunori Yoshimura Department of Obstetrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorTakao Takahashi, Takao Takahashi Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorKenjiro Kosaki, Corresponding Author Kenjiro Kosaki [email protected] Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanDivision of Medical Genetics, Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.Search for more papers by this author Michihiko Aramaki, Michihiko Aramaki Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorIsamu Hokuto, Isamu Hokuto Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorTadashi Matsumoto, Tadashi Matsumoto Department of Obstetrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorHitoshi Ishimoto, Hitoshi Ishimoto Department of Obstetrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorMakoto Inoue, Makoto Inoue Department of Ophthalmology, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorTokuhiro Kimura, Tokuhiro Kimura Department of Pathology, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorYo-ichi Oikawa, Yo-ichi Oikawa Department of Internal Medicine, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorKazushige Ikeda, Kazushige Ikeda Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorYasunori Yoshimura, Yasunori Yoshimura Department of Obstetrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorTakao Takahashi, Takao Takahashi Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanSearch for more papers by this authorKenjiro Kosaki, Corresponding Author Kenjiro Kosaki [email protected] Department of Pediatrics, Keio University School of Medicine, Tokyo, JapanDivision of Medical Genetics, Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.Search for more papers by this author First published: 08 November 2005 https://doi.org/10.1002/ajmg.a.30917Citations: 18Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Barbero P, Ricagni C, Mercado G, Bronberg R, Torrado M. 2004. Choanal atresia associated with prenatal methimazole exposure: Three new patients. Am J Med Genet 129A: 83–86. Clementi M, Di Gianantonio E, Pelo E, Mammi I, Basile RT, Tenconi R. 1999. Methimazole embryopathy: Delineation of the phenotype. Am J Med Genet 83: 43–46. Greenberg F. 1987. Choanal atresia and athelia: Methimazole teratogenicity or a new syndrome? Am J Med Genet 28: 931–934. Johnsson E, Larsson G, Ljunggren M. 1997. Severe malformations in infant born to hyperthyroid woman on methimazole. Lancet 350: 1520. Karlsson FA, Axelsson O, Melhus H. 2002. Severe embryopathy and exposure to methimazole in early pregnancy. J Clin Endocrinol Metab 87: 947–949. Milham S Jr. 1985. Scalp defects in infants of mothers treated for hyperthyroidism with methimazole or carbimazole during pregnancy. Teratology 32: 321. Mujtaba Q, Burrow GN. 1975. Treatment of hyperthyroidism in pregnancy with propylthiouracil and methimazole. Obstet Gynecol 46: 282–286. Ramirez A, Espinosa de los Monteros A, Parra A, De Leon B. 1992. Esophageal atresia and tracheoesophageal fistula in two infants born to hyperthyroid women receiving methimazole (tapazol) during pregnancy. Am J Med Genet 44: 200–202. Sugrue D, Drury MI. 1980. Hyperthyroidism complicating pregnancy: Results of treatment by antithyroid drugs in 77 pregnancies. Br J Obstet Gynaecol 87: 970–975. Vissers LE, van Ravenswaaij CM, Admiraal R, Hurst JA, de Vries BB, Janssen IM, van der Vliet WA, Huys EH, de Jong PJ, Hamel BC, Schoenmakers EF, Brunner HG, Veltman JA, van Kessel AG. 2004. Mutations in a new member of the chromodomain gene family cause charge syndrome. Nat Genet 36: 955–957. Wilson LC, Kerr BA, Wilkinson R, Fossard C, Donnai D. 1998. Choanal atresia and hypothelia following methimazole exposure in utero: A second report. Am J Med Genet 75: 220–222. Winter RM, Baraitser M. 1987. The london dysmorphology database. J Med Genet 24: 509–510. Citing Literature Volume139A, Issue21 December 2005Pages 156-158 ReferencesRelatedInformation