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BIBTEX RIS

PReS-FINAL-2357: Effects of anti-melanocyte stimulating hormone in murine pristine-induced lupus

2013; BioMed Central; Volume: 11; Issue: S2 Linguagem: Inglês

10.1186/1546-0096-11-s2-p347

ISSN

1546-0096

Autores

Tatiana Vasconcelos Peixoto, Suzana Beatriz Veríssimo de Mello, Domingos Alexandre Ciccone Botte, Solange Carrasco, Margarete B. G. Vendramini, Cláudia Goldenstein‐Schainberg,

Tópico(s)

Cytokine Signaling Pathways and Interactions

Resumo

Alfa-melanocyte stimulating hormone (α-MSH) has a variety of biological functions such as downregulation of pro-inflammatory pathways, reduction of skin delayed-type hypersensitivity and blockage of leukocyte migration. Inhibition of experimental disease models development including inflammatory bowel disease and rheumatoid arthritis has been shown, however the immunomodulatory and anti-inflammatory effects of α-MSH on murine lupus remain undetermined.

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