From Translational Neuroscience to Personalized Medicine
2015; Wiley; Volume: 39; Issue: 4 Linguagem: Inglês
10.1111/acer.12667
ISSN1530-0277
AutoresJohn H. Krystal, Stephanie S. O’Malley,
Tópico(s)Pharmacogenetics and Drug Metabolism
ResumoAlcoholism: Clinical and Experimental ResearchVolume 39, Issue 4 p. 585-586 Commentary From Translational Neuroscience to Personalized Medicine John H. Krystal, Corresponding Author John H. Krystal Departments of Psychiatry and Neurobiology , Yale University School of Medicine, New Haven, Connecticut Psychiatry Services , Yale-New Haven Hospital, New Haven, Connecticut Clinical Neuroscience Division , VA National Center for PTSD, VA Connecticut Healthcare System, West Haven, ConnecticutReprint requests: John H. Krystal, MD, Departments of Psychiatry and Neurobiology, Yale University School of Medicine, 300 George St, Suite #901, New Haven, CT 06511; Tel.: 203-785-6396; Fax: 203-785-6196; E-mail: [email protected]Search for more papers by this authorStephanie S. O'Malley, Stephanie S. O'Malley Departments of Psychiatry and Neurobiology , Yale University School of Medicine, New Haven, Connecticut Substance Abuse Treatment Unit , Connecticut Mental Health Center, New Haven, ConnecticutSearch for more papers by this author John H. Krystal, Corresponding Author John H. Krystal Departments of Psychiatry and Neurobiology , Yale University School of Medicine, New Haven, Connecticut Psychiatry Services , Yale-New Haven Hospital, New Haven, Connecticut Clinical Neuroscience Division , VA National Center for PTSD, VA Connecticut Healthcare System, West Haven, ConnecticutReprint requests: John H. Krystal, MD, Departments of Psychiatry and Neurobiology, Yale University School of Medicine, 300 George St, Suite #901, New Haven, CT 06511; Tel.: 203-785-6396; Fax: 203-785-6196; E-mail: [email protected]Search for more papers by this authorStephanie S. O'Malley, Stephanie S. O'Malley Departments of Psychiatry and Neurobiology , Yale University School of Medicine, New Haven, Connecticut Substance Abuse Treatment Unit , Connecticut Mental Health Center, New Haven, ConnecticutSearch for more papers by this author First published: 06 February 2015 https://doi.org/10.1111/acer.12667Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References Anton RF, O'Malley SS, Ciraulo DA, Cisler RA, Couper D, Donovan DM, Gastfriend DR, Hosking JD, Johnson BA, LoCastro JS, Longabaugh R, Mason BJ, Mattson ME, Miller WR, Pettinati HM, Randall CL, Swift R, Weiss RD, Williams LD, Zweben A, COMBINE Study Research Group (2006) Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA 295: 2003–2017. 10.1001/jama.295.17.2003 CASPubMedWeb of Science®Google Scholar Anton RF, Oroszi G, O'Malley S, Couper D, Swift R, Pettinati H, Goldman D (2008) An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry 65: 135–144. 10.1001/archpsyc.65.2.135 CASPubMedWeb of Science®Google Scholar Cuthbert BN, Insel TR (2013) Toward the future of psychiatric diagnosis: the seven pillars of RDoC. BMC Med 11: 126. 10.1186/1741-7015-11-126 PubMedWeb of Science®Google Scholar Gueorguieva R, Wu R, Donovan D, Rounsaville BJ, Couper D, Krystal JH, O'Malley SS (2010) Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study. Drug Alcohol Depend 107: 221–229. 10.1016/j.drugalcdep.2009.10.017 CASPubMedWeb of Science®Google Scholar Krystal JH, State MW (2014) Psychiatric disorders: diagnosis to therapy. Cell 157: 201–214. 10.1016/j.cell.2014.02.042 CASPubMedWeb of Science®Google Scholar Litten RZ, Ryan ML, Falk DE, Reilly M, Fertig JB, Koob GF (2015) Heterogeneity of alcohol use disorder: understanding mechanisms to advance personalized treatment. Alcohol Clin Exp Res doi: 10.1111/acer.12669 10.1111/acer.12669 PubMedWeb of Science®Google Scholar Wikiquote (2014) Alan Kay. Available at: http://en.wikiquote.org/wiki/Alan_Kay. Accessed November 21, 2014. Google Scholar Volume39, Issue4April 2015Pages 585-586 ReferencesRelatedInformation
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