Revisão Revisado por pares

The Glial Fibrillary Acidic Protein: The Major Protein Constituent of Glial Filaments

1982; Wiley; Volume: 15; Issue: s9 Linguagem: Inglês

10.1111/j.1365-3083.1982.tb03757.x

ISSN

1365-3083

Autores

Lawrence F. Eng,

Tópico(s)

Alzheimer's disease research and treatments

Resumo

Scandinavian Journal of ImmunologyVolume 15, Issue s9 p. 41-51 The Glial Fibrillary Acidic Protein: The Major Protein Constituent of Glial Filaments L. F. ENG, L. F. ENG Department of Pathology, VA Medical Center and Stanford University, School of Medicine, Stanford, California, USA.Search for more papers by this author L. F. ENG, L. F. ENG Department of Pathology, VA Medical Center and Stanford University, School of Medicine, Stanford, California, USA.Search for more papers by this author First published: November 1982 https://doi.org/10.1111/j.1365-3083.1982.tb03757.xCitations: 32AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Antanitus, D.S., Choi, B.H. & Lapham, L.W. Immunofluorescence staining of astrocytes in vitro using antiserum to glial fibrillary acidic protein. Brain Res., 89, 363, 1975. 10.1016/0006-8993(75)90729-5 CASPubMedWeb of Science®Google Scholar 2 Antanitus, D.S., Choi, B.H. & Lapham, L.W. The demonstration of glial fibrillary acidic protein in the cerebrum of the human fetus by indirect immunofluorescence. Brain Res., 103, 613, 1976. 10.1016/0006-8993(76)90464-9 CASPubMedWeb of Science®Google Scholar 3 Benda, P., Mori, T. & Sweet, W.H. Demonstration of an astrocyte-specific cerebroprotein by an immunofluorescence study of human brain tumors. J. Neurosurg., 33, 281, 1970. 10.3171/jns.1970.33.3.0281 CASPubMedWeb of Science®Google Scholar 4 Benitz, W.E., Dahl, D., Williams, K. & Bignami, A. CNS fractions enriched in nerve and glial fibers. Immunological and biochemical studies. J. Neuropath, exp. Neurol., 35, 345, 1976. 10.1097/00005072-197605000-00098 Web of Science®Google Scholar 5 Benitz, W.E., Dahl, D., Williams, K.W. & Bignami, A. The protein composition of glial and nerve fibers. FEBS Lett., 66, 285, 1976. 10.1016/0014-5793(76)80523-6 CASPubMedWeb of Science®Google Scholar 6 Bignami, A. & Dahl, D. Differentiation of astrocytes in the cerebellar cortex and the pyramidal tracts of the newborn rat. An immunofluorescence study with antibodies to a protein specific to astrocytes. Brain Res., 49, 393, 1973. 10.1016/0006-8993(73)90430-7 CASPubMedWeb of Science®Google Scholar 7 Bignami, A. & Dahl, D. Astrocyte-specific protein and neuroglial differentiation. An immunofluorescence study with antibodies to the glial fibrillary acidic protein. J. comp. Neur., 153, 27, 1974. 10.1002/cne.901530104 PubMedWeb of Science®Google Scholar 8 Bignami, A. & Dahl, D. Astrocyte-specific protein and radial glia in the cerebral cortex of newborn rat. Nature, 252, 55, 1974. 10.1038/252055a0 CASPubMedWeb of Science®Google Scholar 9 Bignami, A. & Dahl, D. Glial fibrillary acidic protein in mutant mice with deficiency of myelination: quaking and jimpy. Acta Neuropath. (BerL), 28, 269, 1974. 10.1007/BF00719032 CASPubMedWeb of Science®Google Scholar 10 Bignami, A. & Dahl, D. The development of Bergmann glia in mutant mice with cerebellar malformations: reeler, staggerer and weaver. Immunofluorescence study with antibodies to the glial fibrillary acidic protein. J. comp. Neur., 155, 219, 1974. 10.1002/cne.901550207 CASPubMedWeb of Science®Google Scholar 11 Bignami, A. & Dahl, D. Degradation of glial fibrillary acidic protein in multiple sclerosis plaques (abstract). Lab. Invest, 32, 442, 1975. Web of Science®Google Scholar 12 Bignami, A. & Dahl, D. Astroglial protein in the developing spinal cord of the chick embryo. Develop. Biol., 44, 204, 1975. 10.1016/0012-1606(75)90388-7 CASPubMedWeb of Science®Google Scholar 13 Bignami, A. & Dahl, D. The astroglial response to stabbing. Immunofluorescence studies with antibodies to astrocyte-specific protein (GFA) in mammalian and submammalian vertebrates. Neuropath, appl. Neurobiol, 2, 99, 1976. 10.1111/j.1365-2990.1976.tb00488.x Web of Science®Google Scholar 14 Bignami, A. & Dahl, D. Specificity of the glial fibrillary acidic protein for astroglia,. J. Histochem. Cytochem., 25, 466, 1977. 10.1177/25.6.69656 CASPubMedWeb of Science®Google Scholar 15 Bignami, A. & Dahl, D. Glial fibrillary acidic protein (GFA) and neuroglial scarring: A review. In H.F. Naftchi (ed.) Recent Advances in Spinal Cord Injury, Spectrum Publishers, New York, 1977. Google Scholar 16 Bignami, A. & Dahl, D. Isolation of GFA protein from normal brain–a comment. J. Histochem. Cytochem., 27, 693, 1979. 10.1177/27.2.376689 CASPubMedWeb of Science®Google Scholar 17 Bignami, A., Dahl, D. & Rueger, D.G. Isolation of neurofilament and glial filament proteins from water and urea extracts of nerve tissue. p. 153 in S. Roberts, A. Lajtha & W.H. Gispen (eds.) Mechanisms, Regulation, and Special Functions of Protein Synthesis in the Brain. Elsevier, Amsterdam, 1977. Google Scholar 18 Bignami, A., Eng, L.F., Dahl, D. & Uyeda, C.T. Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence. Brain Res., 43, 429, 1972. 10.1016/0006-8993(72)90398-8 CASPubMedWeb of Science®Google Scholar 19 Bignami, A., Forno, L. & Dahl, D. The neuroglial response to injury following spinal cord transection in the goldfish. Exp. Neurol., 44, 60, 1974. 10.1016/0014-4886(74)90046-6 PubMedWeb of Science®Google Scholar 20 Bignami, A. & Stoolmiller, A.C. Astroglia-specific protein (GFA) in clonal cell lines derived from the G26 mouse glioma. Brain Res., 163, 353, 1979. 10.1016/0006-8993(79)90366-4 CASPubMedWeb of Science®Google Scholar 21 Bissell, M.G., Eng, L.F., Herman, M.M., Bensch, K.G. & Miles, L.E.M. Quantitative increase of neuroglia-specific GFA protein in rat C-6 glioma cells in vitro. Nature, 255, 633, 1975. 10.1038/255633a0 CASPubMedWeb of Science®Google Scholar 22 Bissell, M.G., Rubinstein, L.J., Bignami, A. & Herman, M.M. Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis. Brain Res. 82, 77, 1974. 10.1016/0006-8993(74)90894-4 CASPubMedWeb of Science®Google Scholar 23 Bock, E. Nervous system specific proteins. J. Neurochem., 30, 7, 1978. 10.1111/j.1471-4159.1978.tb07028.x CASPubMedWeb of Science®Google Scholar 24 Bock, E. & Hamberger, A. Immunoelectrophoretic determination of brain-specific antigens in bulk-prepared neuronal and glial cells,. Brain Res., 112, 329, 1976. 10.1016/0006-8993(76)90287-0 CASPubMedWeb of Science®Google Scholar 25 Bock, E., Jorgensen, O.S., Dittman, L. & Eng, L.F. Determination of brain-specific antigens in short term cultivated rat astroglial cells and in rat synaptosomes. J. Neurochem., 25, 867, 1975. 10.1111/j.1471-4159.1975.tb04419.x CASPubMedWeb of Science®Google Scholar 26 Bock, E., Moller, M., Nissen, C. & Sensenbrenner, M. Glial fibrillary acidic protein in primary astroglial cell cultures derived from newborn rat brain. FEBS Lett., 83, 207, 1977. 10.1016/0014-5793(77)81006-5 CASPubMedWeb of Science®Google Scholar 27 Bock, E., Rasmussen, S., Moller, M. & Ebbesen, P. Demonstration of a protein immunochemically related to glial fibrillary acidic protein in human fibroblasts in culture. FEBS Lett., 83, 212, 1977. 10.1016/0014-5793(77)81007-7 CASPubMedWeb of Science®Google Scholar 28 Bogoch, S. Brain glycoprotein 10B: further evidence of the "sign-post" role of brain glycoproteins in cell recognition, its change in brain tumor, and the presence of a "distance factor", pp. 39–52 in Functional and Structural Proteins of the Nervous System. Plenum Publishing, New York, 1972. 10.1007/978-1-4684-6979-0_5 Google Scholar 29 Bogoch, S. Astrocytin: purified immunologically active component of brain glycoprotein 10B (abstract). ISN Meeting, p. 173, 1973. Google Scholar 30 Braak, E., Drenckhahn, D., Unsicker, K., Groschel-Stewart, U. & Dahl, D. Distribution of myosin and the glial fibrillary acidic protein (GFA Protein) in rat spinal cord and in the human frontal cortex as revealed by immunofluorescence microscopy. Cell Tiss. Res., 191, 493, 1978. 10.1007/BF00219811 CASPubMedWeb of Science®Google Scholar 31 Cain, D.F., Ball, E.D. & Dekaban, A.S. Proteins of human brain tissue obtained during surgical procedures. J. Neurochem., 23, 561, 1974. 10.1111/j.1471-4159.1974.tb06060.x CASPubMedWeb of Science®Google Scholar 32 Chan, P.H., Huston, J.S., Dahl, D. & Bignami, A. Purification and initial characterization of astroglial protein from bovine brain. Fed. Proc., 34, 224, 1975. Web of Science®Google Scholar 33 Chan, P.H., Huston, J.S., Moo-Penn, W.F., Dahl, D. & Bignami, A. Biochemical studies related to CNS regeneration: isolation and partial characterization of ureasoluble gliofibrillary acidic protein from bovine brain. pp. 496–524 in Proceedings of the Second Annual Maine Biomedical Science Symposium, V. II. University of Maine Press, 1977. Google Scholar 34 Choi, B.H. & Lapham, L.W. Radial glia in the human fetal cerebrum: a combined golgi, immunofluorescent and electron microscopic study. Brain Res., 148, 295, 1978. 10.1016/0006-8993(78)90721-7 CASPubMedWeb of Science®Google Scholar 35 Cohen, J., Woodhams, P.L. & Balazs, R. Preparation of viable astrocytes from the developing cerebellum. Brain Res., 161, 503, 1979. 10.1016/0006-8993(79)90679-6 PubMedWeb of Science®Google Scholar 36 Conley, F.K. The immunocytochemical localization of GFA protein in experimental murine CNS tumors. Acta Neuropathol, 45, 9, 1979. 10.1007/BF00691799 CASPubMedWeb of Science®Google Scholar 37 Dahl, D. Glial fibrillary acidic protein from bovine and rat brain. Degradation in tissues and homogenates. Biochim. Biophys. Acta, 420, 142, 1976. 10.1016/0005-2795(76)90353-6 CASPubMedWeb of Science®Google Scholar 38 Dahl, D. Isolation and initial characterization of glial fibrillary acidic protein from chicken, turtle, frog, and fish central nervous system. Biochim. Biophys. Acta, 446, 41, 1976. 10.1016/0005-2795(76)90095-7 CASPubMedWeb of Science®Google Scholar 39 Dahl, D. & Bignami, A. Glial fibrillary acidic protein from normal human brain. Purification and properties. Brain Res., 57, 343, 1973. 10.1016/0006-8993(73)90141-8 CASPubMedWeb of Science®Google Scholar 40 Dahl, D. & Bignami, A. Immunochemical and immunofluorescence studies of the glial fibrillary acidic protein in vertebrates. Brain Res., 61, 279, 1973. 10.1016/0006-8993(73)90533-7 CASPubMedWeb of Science®Google Scholar 41 Dahl, D. & Bignami, A. Heterogeneity of the glial fibriliary acidic protein in gliosed human brains. J. Neurol. Sci., 23, 551, 1974. 10.1016/0022-510X(74)90027-6 CASPubMedWeb of Science®Google Scholar 42 Dahl, D. & Bignami, A. Glial fibrillary acidic protein from normal and gliosed human brain. Demonstration of multiple related polypeptides. Biochim. Biophys. Acta, 386, 41, 1975. 10.1016/0005-2795(75)90244-5 CASPubMedWeb of Science®Google Scholar 43 Dahl, D. & Bignami, A. Protein differences associated with the loss of myelinated axons and fibrillary gliosis in rat optic nerves following Wallerian degeneration. FEBS Lett., 51, 313, 1975. 10.1016/0014-5793(75)80915-X CASPubMedWeb of Science®Google Scholar 44 Dahl, D. & Bignami, A. Isolation from peripheral nerve a protein similar to GFA protein. Fed. Proc., 35, 1766, 1976. Web of Science®Google Scholar 45 Dahl, D. & Bignami, A. Isolation from peripheral nerve of a protein similar to the glial fibrillary acidic protein. FEBS Lett., 66, 281, 1976. 10.1016/0014-5793(76)80522-4 CASPubMedWeb of Science®Google Scholar 46 Dahl, D. & Bignami, A. Immunogenic properties of the glial fibrillary acidic protein. Brain Res., 116, 150, 1976. 10.1016/0006-8993(76)90257-2 CASPubMedWeb of Science®Google Scholar 47 Dahl, D. & Bignami, A. Effect of sodium dodecyl sulfate on the immunogenic properties of the glial fibrillary acidic protein. J. Immunol. Meth., 17, 201, 1977. 10.1016/0022-1759(77)90102-8 CASPubMedWeb of Science®Google Scholar 48 Davison, P.F. Neuronal fibrillar proteins and axoplasmic transport. Brain Res., 100, 73, 1975. 10.1016/0006-8993(75)90242-5 CASPubMedWeb of Science®Google Scholar 49 Davison, P.F. & Hong, B.S. Filaments in nervous tissue and muscle cells (abstract), p. 106 in Sixth International Meeting of the International Society for Neurochemistry, Copenhagen, Denmark, 1977. Web of Science®Google Scholar 50 Davison, P.F. & Winslow, B. The protein subunit of calf brain neurofilament. J. Neurobiol., 5, 119, 1974. 10.1002/neu.480050204 CASPubMedWeb of Science®Google Scholar 51 Deck, J.H., Eng, L.F. & Bigbee, J. A preliminary study of glioma morphology using the peroxidase-anti-peroxidase method for the GFA protein. J. Neuropath. exp. Neurol., 35, 362, 1976. 10.1097/00005072-197605000-00132 Web of Science®Google Scholar 52 Deck, J.H.N., Eng, L.F., Bigbee, J. & Woodcock, S.M. The role of glial fibrillary acidic protein in the diagnosis of central nervous system tumours. Acta Neuropathol. (Berl.), 42, 183, 1978. 10.1007/BF00690355 CASPubMedWeb of Science®Google Scholar 53 Delpech, B. & Buffe, D. Etude immunochimique des extraits salins du cerveau humain. Ann. Inst. Pasteur, 122, 331, 1972. CASPubMedWeb of Science®Google Scholar 54 Delpech, B., Chauzy, C., Delpech, A. & Maunoury, R. Protides of the biological fluids. pp. 363–366 in H. Peters (ed.) 22nd Symposium. Pergamon Press, Oxford and New York, 1975. Google Scholar 55 Delpech, B. & Delpech, A. Caracterisation immunochimique d'un antigene neurospecifique d'espece. Etude quantitative et localisation histologique chez le rat. Immunochem., 12, 691, 1975. 10.1016/0019-2791(75)90217-7 CASPubMedWeb of Science®Google Scholar 56 Delpech, B., Delpech, A., Vidard, M.N., Girard, N., Tayot, J., Clement, J.C. & Creissard, P. Glial fibrillary acidic protein in tumours of the nervous system. Br. J. Cancer, 37, 33, 1978. 10.1038/bjc.1978.5 CASPubMedWeb of Science®Google Scholar 57 Delpech, B., Vidard, M.N., Schlosser, M. & Hernot, C. Quelques proprietes d'une glycoproteine antigeniquement specifique du systeme nerveux. Cr. Soc. Biol., 167, 1029, 1973. CASPubMedWeb of Science®Google Scholar 58 DeVries, G.H., Eng, L.F., Lewis, D.H. & Hadfield, M.G. The protein composition of bovine myelin-free axons. Biochim. Biophys. Acta, 439, 133, 1976. 10.1016/0005-2795(76)90169-0 CASPubMedWeb of Science®Google Scholar 59 DeVries, G.H., Hatfield, M.G., Eng, L.F. & Liwnicz, B.H. Protein composition of bovine myelin-free axons. 3rd Annual Meeting of the Society for Neuroscience, San Diego, California, 1973. Google Scholar 60 DeVries, G.H., Norton, W.T. & Raine, C.S. Axons: isolation from mammalian central nervous system. Science, 175, 1370, 1971. 10.1126/science.175.4028.1370 PubMedWeb of Science®Google Scholar 61 Dittmann, L., Axelsen, N.H., Norgaard-Pedersen, B. & Bock, E. Antigens in human glioblastomas and meningiomas: search for tumour and onco-foetal antigens. Estimation of S-100 and GFA protein. Br. J. Cancer, 35, 135, 1977. 10.1038/bjc.1977.20 CASPubMedWeb of Science®Google Scholar 62 Duffy, P.E., Graf, L., & Rapport, M.M. Identification of glial fibrillary acidic protein by the immunoperoxidase method in human brain tumors. J. Neuropath. Exp. Neurol., 36, 645, 1977. 10.1097/00005072-197707000-00001 CASPubMedWeb of Science®Google Scholar 63 Duffy, P.E., Graf, L., Huang, Y.-Y. & Rapport, M.M. Glial fibrillary acidic protein in ependymomas and other brain tumors. J. neurol. Sci., 40, 133, 1979. 10.1016/0022-510X(79)90199-0 CASPubMedWeb of Science®Google Scholar 64 Eng, L.F. Chemical characterization of the glial fibrillary acidic protein. Fed. Proc., 32, 485, 1973. Google Scholar 65 Eng, L.F. Reply to the comments of Bignami & Dahl. J. Histochem. Cytochem., 27, 694, 1979. Web of Science®Google Scholar 66 Eng, L.F. & Bigbee, J.W. Immunohistochemistry of nervous system-specific antigens. pp. 43–98 in B.W. Agranoff & M.H. Aprison (eds.) Advances in Neurochemistry Vol. 3. Plenum Press, New York, 1978. 10.1007/978-1-4615-8240-3_2 Google Scholar 67 Eng, L.F., Burkstaller, M., Bigbee, J., Kosek, J.C. & Kies, M.W. Immunohistologic comparison of the glial fibrillary acidic protein and myelin basic protein in the myelinating rat brain (abstract), p. 41 in Fifth International Meeting of the International Society for Neurochemistry, Barcelona, Spain, 1975. Google Scholar 68 Eng, L.F., DeVries, G.H., Lee, Y.L., Bigbee, J.W. & Fukayama, G. Recent studies of the glial fibrillary acidic (GFA) protein (abstract), p. 100 in Sixth International Meeting of the International Society for Neurochemistry. Copenhagen, Denmark, 1977. Google Scholar 69 Eng, L.F., DeVries, G.H., Lewis, D.L. & Bigbee, J. Specific antibody to the major 47,000 MW protein fraction of bovine myelin-free axons. Fed. Proc., 35, 1766, 1976. Web of Science®Google Scholar 70 Eng, L.F., Gerstl, B. & Vanderhaeghen, J.J. A study of proteins in old multiple sclerosis plaques. Trans. Amer. Soc. Neurochem. 1, 42, 1970. Google Scholar 71 Eng, L.F. & Kosek, J.C. Light and electron microscopic localization of the glial fibrillary acidic protein and S-100 protein by immunoenzymatic techniques. Trans. Amer. Soc. Neurochem., 5, 160, 1974. Google Scholar 72 Eng, L.F., Kosek, J.C., Forno, L., Deck, J. & Bigbee, J. Immunohistochemistry of brain proteins in fixed, paraffin-embedded tissue. Trans. Amer. Soc. Neurochem., 7, 211, 1976. Google Scholar 73 Eng, L.F., Kosek, J.C. & Miles, L.E.M. Immunohistologic and immunoradiometric study with brain specific proteins. Trans. Amer. Soc. Neurochem., 6, 75, 1975. Google Scholar 74 Eng, L.F., Lee, Y.L. & Fukayama, G. Isolation of glial fibrillary acidic (GFA) protein from bovine spinal cord. Trans. Amer. Soc. Neurochem., 10, 126, 1979. Google Scholar 75 Eng, L.F., Lee, Y.L., Fukayama, G. & Bigbee, J. GFA protein content of developing normal and jimpy mouse dervous tissue. Trans. Amer. Soc. Neurochem., 9, 63, 1978. Google Scholar 76 Eng, L.F., Lee, Y.L., Kies, M.W. & Miles, L.E.M. Analysis of nervous system-specific proteins by 2-site immunoradiometric assays. Sixth International Meeting of the International Society for Neurochemistry, Copenhagen, Denmark, 1977. Google Scholar 77 Eng, L.F., Lee, Y.L. & Miles, L.E.M. 2-Site immunoradio-metric assay for glial fibrillary acidic protein in human cerebral spinal fluid (abstract), p. 302 in Fifth International Meeting of the International Society for Neurochemistry, Barcelona, Spain, 1975. Google Scholar 78 Eng, L.F., Lee, Y.L. & Miles, L.E.M. Measurement of glial fibrillary acidic protein by a two-site immunoradiometric assay. Anal. Biochem., 71, 243, 1976. 10.1016/0003-2697(76)90033-6 CASPubMedWeb of Science®Google Scholar 79 Eng, L.F. & Rubinstein, L.J. Contribution of immunohistochemistry to diagnostic problems of human cerebral tumors. J. Histochem. Cytochem., 26, 513, 1978. 10.1177/26.7.357640 CASPubMedWeb of Science®Google Scholar 80 Eng, L.F. & Uyeda, C.T. Immunologic specificity of the water-soluble and -insoluble glial fibrillary acidic protein. Trans. Amer. Soc. Neurochem., 4, 79, 1973. Google Scholar 81 Eng, L.F., Vandergaeghen, J.J., Bignami, A. & Gerstl, B. An acidic protein isolated from fibrous astrocytes. Brain Res., 28, 351, 1971. 10.1016/0006-8993(71)90668-8 CASPubMedWeb of Science®Google Scholar 82 Gheuens, J., Lowenthal, A., Karcher, D. & Noppe, M. Similarities between the nervous tissue proteins a-albumin and glial fibrillary acidic protein. p. 257 in G. Franck, L. Hertz, E. Schoffeniels & D.B. Tower (eds.) Dynamic Properties of Glial Cells. Pergamon Press, Oxford, 1978. Google Scholar 83 Gilden, D.H., Wroblewska, Z., Eng, L.F. & Rorke, L.B. Human brain in tissue culture. J. Neurol. Sci., 29, 177, 1976. 10.1016/0022-510X(76)90169-6 CASPubMedWeb of Science®Google Scholar 84 Goldman, J.E., Schaumburg, H.H. & Norton, W.T. Isolation and characterization of glial filaments and neurofilaments from human brain. Similarity of the major protein components. J. Cell biol., 78, 426, 1978. 10.1083/jcb.78.2.426 CASPubMedWeb of Science®Google Scholar 85 Herman, M.M. & VandenBerg, S.R. Neoplastic neuroepithelial differentiation in an experimental transplantable teratoma. In G.F. Saunders (ed.) Cell Differentiation and Neoplasia. Raven Press, New York, 1978. Google Scholar 86 Hoffman, P.N. & Lasek, R.J. The slow component of axonal transport. J. Cell Biol., 66, 351, 1975. 10.1083/jcb.66.2.351 CASPubMedWeb of Science®Google Scholar 87 Hong, B.S. & Davison, P.F. Characterization of mammalian neurofilament protein. Fed. Proc., 35, 1766, 1976. Web of Science®Google Scholar 88 Huneeus, F.C. & Davison, P.F. Fibrillary proteins from squid axons. I. Neurofilament protein. J. mol. Biol., 52, 415, 1970. 10.1016/0022-2836(70)90410-9 CASPubMedWeb of Science®Google Scholar 89 Huston, J.S. & Bignami, A. Structural properties of GFA protein from bovine brain. Fed. Proc., 35, 1482, 1976. Web of Science®Google Scholar 90 Huston, J.S. & Bignami, A. Structural properties of the glial fibrillary acidic: evidence for intermolecular disulfide bonds. Biochim. Biophys. Acta, 493, 93, 1977. 10.1016/0005-2795(77)90262-8 CASPubMedWeb of Science®Google Scholar 91 Jacque, C.M., Baumann, N.A. & Bock, E. Quantitative studies of the brain specific antigens GFA, 14–3–2, Synaptin C1, D1, D2, D3 and D5 in jimpy mouse. Neurosci, Lett., 3, 41, 1976. 10.1016/0304-3940(76)90097-5 CASPubMedWeb of Science®Google Scholar 92 Jacque, C.M., Jorgensen, O.S., Baumann, N.A. & Bock, E. Brain-specific antigens in the quaking mouse during ontogeny. J. Neurochem., 27, 905, 1976. 10.1111/j.1471-4159.1976.tb05153.x CASPubMedWeb of Science®Google Scholar 93 Jacque, C.M., Jorgensen, O.S. & Bock, E. Quantitative studies of the brain specific antigens S-100, GFA, 14–3–2, D1, D2, D3 and C1 in quaking mouse. FEBS Lett., 49, 264, 1974. 10.1016/0014-5793(74)80526-0 CASPubMedWeb of Science®Google Scholar 94 Jacque, C.M., Vinner, C., Kujas, M., Raoul, M., Racadot, J. & Baumann, N.A. Determination of glial fibrillary acidic protein (GFAP) in human brain tumors. J. Neurol. Sci., 35, 147, 1978. 10.1016/0022-510X(78)90107-7 CASPubMedWeb of Science®Google Scholar 95 Johnson, L. & Sinex, F.M. On the relationship of brain filaments to microtubules. J. Neurochem., 22, 321, 1974. 10.1111/j.1471-4159.1974.tb07594.x CASPubMedWeb of Science®Google Scholar 96 Jorgensen, A.O., Subrahmanyan, L., Turnbull, C. & Kalnins, V.I. Localization of the neurofilament protein in neuroblastoma cells by immunofluorescent staining. Proc. nat. Acad. Sci. (USA), 73, 3192, 1976. 10.1073/pnas.73.9.3192 CASPubMedWeb of Science®Google Scholar 97 Kepes, J.J., Rubinstein, L.J. & Eng, L.F. Pleomorphic xanthoastrocytoma. A distinctive meningocerebral glioma of young subjects with relatively favorable prognosis, A study of 12 cases. Cancer, 44, 1839, 1979. 10.1002/1097-0142(197911)44:5 3.0.CO;2-0 PubMedWeb of Science®Google Scholar 98 Kozak, L.P., Dahl, D. & Bignami, A. Glial Fibrillary acidic protein in reaggregating and monolayer cultures of fetal mouse cerebral hemispheres. Brain Res., 150, 631, 1978. 10.1016/0006-8993(78)90828-4 CASPubMedWeb of Science®Google Scholar 99 Kozak, L.P., Eppig, J.J., Dahl, D. & Bignami, A. A cell culture model for the study of neuronal-glial interactions. Prevention of fibrous gliosis by polylysine (abstract). J. Neuropath. exp. Neurol., 36, 610, 1977. 10.1097/00005072-197705000-00077 Web of Science®Google Scholar 100 Kozak, L.P., Eppig, J.J., Dahl, D. & Bignami, A. Ultrastructural and immunohistological characterization of a cell culture model for the study of neuronal-glial interactions. Dev. Biol., 59, 206, 1977. 10.1016/0012-1606(77)90255-X CASPubMedWeb of Science®Google Scholar 101 Lasek, R.J. & Hoffman, P.N. The neuronal cytoskeleton, axonal transport and axonal growth. Cell Motility, C, 1021, 1976. Google Scholar 102 Lee, V., Yen, S.H. & Shelanski, M.L. Biochemical correlates of astrocyte proliferation in the mutant Staggerer mouse. Brain Res., 128, 389, 1977. 10.1016/0006-8993(77)91007-1 CASPubMedWeb of Science®Google Scholar 103 Lee, Y.L., Eng, L.F. & Miles, L.E.M. Extraction and immunologic identity of "soluble" and "insoluble" GFA protein. Trans. Amer. Soc. Neurochem., 7, 240, 1976. Google Scholar 104 Liao, C.L., Eng, L.F., Herman, M.M. & Bensch, K.G. Glial fibrillary acidic protein-solubility characteristics, relation to cell growth phases and cellular localization in rat C-6 glioma cells: an immunoradiometric and immunohistologic study. J. Neurochem., 30, 1181, 1978. 10.1111/j.1471-4159.1978.tb12415.x CASPubMedWeb of Science®Google Scholar 105 Liao, C.L., Herman, M.M., Bensch, K.G. & Eng, L.F. Glial fibrillary acidic protein content in rat C6 glioma cells in vitro. Trans. Amer. Soc. Neurochem., 8, 141, 1977. Google Scholar 106 Liem, R.K.H. & Shelanski, M.L. Identity of the major protein in "native" glial fibrillary acidic protein preparations with tubulin. Brain Res., 145, 196, 1978. 10.1016/0006-8993(78)90811-9 CASPubMedWeb of Science®Google Scholar 107 Liem, R.K.H., Yen, S.H., Salomon, G.D. & Shelanski, M.L. Intermediate filaments in nervous tissue. J. Cell Biol., 79, 637, 1978. 10.1083/jcb.79.3.637 CASPubMedWeb of Science®Google Scholar 108 Lowenthal, A., Noppe, M., Gheuens, J. & Karcher, D. Alpha-albumin (glial fibrillary acidic protein) in normal and pathological human brain and cerebrospinal fluid. J. Neurol., 219, 87, 1978. 10.1007/BF00314391 CASPubMedWeb of Science®Google Scholar 109 Lucas, C.V., Bensch, K.G. & Eng, L.F. In vitro assembly of filaments with glial fibrillary acidic protein. Trans. Amer. Soc. Neurochem., 10, 126, 1979. Google Scholar 110 Ludwin, S.K., Eng, L.F., VandenBerg, S.R., Kosek, J.C. & Herman, M.M. Glial differentiation in an experimental mouse. J. Neuropath. exp. Neurol., 35, 102, 1976. Google Scholar 111 Ludwin, S.K., Kosek, J.C. & Eng, L.F. A morphological comparison of GFA and S-100 proteins in rat brain using the peroxidase-labelled antibody technique adapted for routine histological examination. Trans. Amer. Soc. Neurochem., 6, 84, 1975. Google Scholar 112 Ludwin, S.K., Kosek, J.C. & Eng, L.F. The topographical distribution of S-100 and GFA proteins in the adult rat brain: An immunohistochemical study using horseradish peroxidase-labeled antibodies. J. comp. Neurol., 165, 197, 1976. 10.1002/cne.901650206 CASPubMedWeb of Science®Google Scholar 113 Maunoury, R., Delpech, A., Delpech, B., Vidard, M.N. & Vedrenne, C. Presence of neurospecific antigen NSA 1 in fetal human astrocytes in long-term culture. Brain Res., 112, 383, 1976. 10.1016/0006-8993(76)90292-4 CASPubMedWeb of Science®Google Scholar 114 Maunoury, R., Delpech, A., Delpech, B., Vidard, M.N., Vedrenne, C., Constans, J.P. & Hillereau, J. Localisation de la proteine gliofibrillaire (GFAP) par immunocytochimie dans les tumeurs cerebrales humaines. Neuro-Chirurgie, 23, 173, 1977. CASPubMedWeb of Science®Google Scholar 115 Miles, L.E.M., Bieber, C.P., Eng, L.F. & Lipschitz, D.A. Properties of two-site immunoradiometric (labelled antibody) assay systems. pp. 149–164 in Radioimmunoassay and Related Procedures in Medicine, Vol I. International Atomic Energy Agency, Vienna, 1974. Google Scholar 116 Moller, M., Ingild, A. & Bock, E. Immunohistochemical demonstration of S-100 protein and GFA protein in interstitial cells of rat pineal gland. Brain Res., 140, 1, 1978. 10.1016/0006-8993(78)90234-2 CASPubMedWeb of Science®Google Scholar 117 Mori, T. & Morimoto, K. Astroprotein, An astrocyte-specific cerebroprotein, in normal brain and glioma (abstract), p. 174 in Fourth International Meeting of the International Society for Neurochemistry, Tokyo, 1973. Google Scholar 118 Mori, T. & Morimoto, K. Studies on the identity of astroprotein. Igaku-no-Aywni, 92, 16, 1975. CASGoogle Scholar 119 Mori, T., Morimoto, K., Hayakawa, T., Ushio, Y., Mogami, H. & Sekiguchi, K. Radioimmunoassay of astroprotein (as astrocyte-specific cerebroprotein) in cerebrospinal fluid and its clinical significance. Neurol. Med. Chir. (Tokyo), 18, 25, 1978. 10.2176/nmc.18pt1.25 CASPubMedGoogle Scholar 120 Mori, T., Morimoto, K., Ushio, Y., Hayakawa, T. & Mogami, H. Radioimmunoassay of astroprotein (an astrocyte-specific cerebroprotein) in cerebrospinal fluid from patients with glioma: a preliminary study. Neurol. Medico-Chirurgica, 15, 23, 1975. 10.2176/nmc.15pt1.23 PubMedGoogle Scholar 121 Palfreyman, J.W., Thomas, D.G.T., Ratcliffe, J.G. & Graham, D.I. Glial fibrillary acidic protein (GFAP). Purification from human fibrillary astrocytoma, development and validation of radioimmunoassay for GFAP-like immunoreactivity. J. neurol. Sci., 41, 101, 1979. 10.1016/0022-510X(79)90144-8 CASPubMedWeb of Science®Google Scholar 122 Rodbard, D. & Hutt, D.M. Statistical analysis of radioimmunoassays and immunoradiometric labeled antibody assays: a generalized weighted iterative least-squares method for logistic curve fitting. pp. 165–189 in Radioimmunoassay and Related Procedures in Medicine, Vol I. International Atomic Agency, Vienna, 1974. Google Scholar 123 Rothman, B., Suddith, R.L., Eng, L., Obert, D., Tiffany, E., Werrbach-Perez, K., Perez-Polo, J.R. & Haber, B. Glial properties of a human clonal cell line (abstract). Soc. Neurosci., 3, 527, 1977. Google Scholar 124 Reuger, D.C., Dahl, D. & Bignami, A. Comparison of bovine glial fibrillary acidic protein with tubulin. Brain Res., 153, 188, 1978. 10.1016/0006-8993(78)91143-5 CASPubMedWeb of Science®Google Scholar 125 Rueger, D.C., Dahl, D. & Bignami, A. Purification of a brain specific astroglial protein by immunoaffinity chromatography. Anal. Biochem., 89, 360, 1978. 10.1016/0003-2697(78)90364-0 CASPubMedWeb of Science®Google Scholar 126 Rubinstein, L.J. & Herman, M.M. Studies on the differentiation of human and experimental gliomas in organ culture systems. In J. Hekmatpanah (ed.) Recent Results in Cancer Research, Vol. 51. Springer-Verlag, Berlin, 1975. Google Scholar 127 Schachner, M., Hedley-Whyte, E.T., Hsu, D.W., Schoonmaker, G. & Bignami, A. Ultrastructural localization of glial fibrillary acidic protein in mouse cerebellum by immunoperoxidase labeling. J. Cell Biol., 75, 67, 1977. 10.1083/jcb.75.1.67 CASPubMedWeb of Science®Google Scholar 128 Schachner, M., Ruberg, M.Z. & Carnow, T.B. Histological localization of nervous-system antigens in the cerebellum by immunoperoxidase labeling. Brain Res. Bull., 1, 367, 1976. 10.1016/0361-9230(76)90030-7 CASPubMedWeb of Science®Google Scholar 129 Schachner, M., Smith, C. & Schoonmaker, G. Immunological distinction between neurofilament and glial fibrillary acidic protein by mouse antisera and their immunohistological characterization. Dev. Neurosci., 1, 1, 1978. 10.1159/000112548 CASPubMedWeb of Science®Google Scholar 130 Schlaepfer, W.W., Freeman, L.A. & Eng, L.F. Studies of human and bovine spinal nerve roots and the evagination of CNS tissues into the nerve root entry zone. Brain Res., 177, 219, 1979. 10.1016/0006-8993(79)90773-X CASPubMedWeb of Science®Google Scholar 131 Schlaepfer, W.W. & Lynch, R.G. Immunofluorescent studies of neurofilaments in the peripheral and central nervous systems of rats and humans. J. Neuropath. exp. Neurol., 35, 345, 1976. 10.1097/00005072-197605000-00099 Web of Science®Google Scholar 132 D.J. Schneider, (ed.) pp. 67–94 in Proteins of the Nervous System, Raven Press, New York, 1973. Google Scholar 133 Shelanski, M.L., Albert, S., DeVries, G.H. & Norton, W.T. Isolation of filaments from brain. Science, 174, 1242, 1971. 10.1126/science.174.4015.1242 CASPubMedWeb of Science®Google Scholar 134 Siegel, M.W. & Eng, L.F. Post-embedding immunocytochemical study at the electron microscopic level. Trans. Amer. Soc. Neurochem., 10, 125, 1979. Google Scholar 135 Sipe, J.C., Rubinstein, L.J., Herman, M.M. & Bignami, A. Ethylnitrosourea-induced astrocytomas. Morphological observations on rat tumors maintained in tissue and organ culture systems. Lab. Inv., 31, 571, 1975. Web of Science®Google Scholar 136 Uyeda, C.T., Eng, L.F. & Bignami, A. Immunological study of the glial fibrillary acidic protein. Brain Res., 37, 81, 1972. 10.1016/0006-8993(72)90347-2 CASPubMedWeb of Science®Google Scholar 137 VandenBerg, S.R., Herman, M.M., Ludwin, S.K. & Bignami, A. An experimental mouse testicular teratoma as a model for neuroepithelial neoplasia and differentiation. I. Light microscopic and tissue and organ culture observations. Amer. J. Path., 79, 147, 1975. CASPubMedWeb of Science®Google Scholar 138 VandenBerg, S.R., Hickey, J.E. & Herman, M.M. Brain-associated cell surface antigens on neuroepithelial cells in a transplantable mouse teratoma. Acta Neuropath., 39, 281, 1977. 10.1007/BF00691708 CASPubMedWeb of Science®Google Scholar 139 VandenBerg, S.R., Ludwin, S.K., Herman, M.M. & Bignami, A. In vitro astrocytic differentiation from embryoid bodies of an experimental mouse testicular teratoma. Amer. J. Path., 83, 197, 1976. CASPubMedWeb of Science®Google Scholar 140 Van der Meulen, J.D.M., Houfhoff, H.J. & Ebels, E.J. Glial fibrillary acidic protein in human gliomas. Neuropath. appl. Neurobiol., 4, 177, 1978. 10.1111/j.1365-2990.1978.tb00534.x CASPubMedWeb of Science®Google Scholar 141 Velasco, M.E., Dahl, D., Roessmann, U. & Gambetti, P. Immunohistochemical localization of glial fibrillary acidic protein in human glial neoplasms. J. Neuropath. exp. Neurol., 37, 703, 1978. 10.1097/00005072-197809000-00407 Web of Science®Google Scholar 142 Vidard, M-N., Girard, N., Chauzy, C., Delpech, B., Delpech, A., Maunoury, R. & Laumonier, R. Disparition de la proteine gliofibrillaire (GFA) au ocurs de la culture de cellules de glioblastomes. C.r. Acad. Sci. (Paris), 286, 1837, 1978. CASPubMedWeb of Science®Google Scholar 143 Vraa-Jensen, J., Herman, M.M., Rubinstein, L.J. & Bignami, A. In vitro characteristics of a fourth ventricle ependymoma maintained in organ culture systems: light and electron microscopy observations. Neuropath. appl. Neurobiol., 2, 349, 1976. 10.1111/j.1365-2990.1976.tb00509.x Web of Science®Google Scholar 144 Wisniewski, H.M. & Soifer, D. Neurofibrillary pathology: current status and research perspectives. Mech. Aging Develop., 9, 119, 1979. 10.1016/0047-6374(79)90125-8 CASPubMedWeb of Science®Google Scholar 145 Yen, S.H., Dahl, D., Schachner, M. & Shelanski, M.L. Biochemistry of the filaments of brain. Proc. Nat. Acad. Sci. (USA), 73, 529, 1976. 10.1073/pnas.73.2.529 CASPubMedWeb of Science®Google Scholar 146 Zomzely-Neurath, C.Z. & Keller, A. Nervous system-specific proteins of vertebrates (a search for functions and physiological roles). Neurochem. Res., 2, 353, 1977. 10.1007/BF00965461 CASPubMedWeb of Science®Google Scholar Citing Literature Volume15, Issues9November 1982Pages 41-51 ReferencesRelatedInformation

Referência(s)