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Stochastic versus deterministic variability in simple neuronal circuits: II. Hippocampal slice

1994; Elsevier BV; Volume: 67; Issue: 2 Linguagem: Inglês

10.1016/s0006-3495(94)80527-2

1542-0086

Steven J. Schiff, Kristin K. Jerger, Taeun Chang, Timothy Sauer, Peter G. Aitken,

Chaos control and synchronization

Long time seies of Schaffer caeral to CAl pyramidl l prsyrapticvoleys (stratu raIaum) and spikes (sam aa)w evoked (driven) in rat oampa slices.Frm the driven CAl region in nrmal [K+lperfusate, bo apte an iut-ou f spie ampide ded by the prsy voley ampltude were anayzed.Raising [(+ in the fusion to 8.5 mM, slices were indrced to buS fire in CA3 and long tine series of interburst intals were re d.Thretests for deinism were applied o these sries: a discrete adaptation of a bocal flow appach, a local disprsion appach, and nonear redction.Surrogate data were generated to serve as mnatmatl and sAtistic conrls.Al of the ie (6J6) and inut-out (6J6) tine series from the rmwmal [K+J driven circuitry were stochastic by al three mehdxs.Althogh most of the time series (516) from the a?noiTxisy burting hjig [K+] state failed to ate evkidnce of , one (1i ) of tese tine series cdid dem- onste si iicn determinis.This singe binsance p could not be acoeted for by the linear oelaion in these dat INTRODUCTONIn the preceding paper, we examined monosynaptic spinal cord reflex variability for evidence of determinism.It was noted that in the spinali state, when the reflex crcuitry is fairly well isolated from the rest of the nervous system, the