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Tumor Inhibitors XIX

1967; Elsevier BV; Volume: 56; Issue: 3 Linguagem: Inglês

10.1002/jps.2600560325

1520-6017

S. Morris Kupchan, R.J. Hemingway, Jane C. Hemingway,

Cancer therapeutics and mechanisms

An alcoholic extract of Libocedrus decurrens Torr. was found to show significant inhibitory activity when tested in vitro against cells derived from human carcinoma of the nasopharynx (KB). Systematic fractionation of the extract led to the isolation and characterization of desoxypodophyllotoxin as the active principle. An alcoholic extract of Libocedrus decurrens Torr. was found to show significant inhibitory activity when tested in vitro against cells derived from human carcinoma of the nasopharynx (KB). Systematic fractionation of the extract led to the isolation and characterization of desoxypodophyllotoxin as the active principle.