Outbreak of acute pulmonary histoplasmosis in members of a wagon train
1981; Elsevier BV; Volume: 71; Issue: 5 Linguagem: Inglês
10.1016/0002-9343(81)90361-2
ISSN1555-7162
AutoresTracy L. Gustafson, Leo Kaufman, Robert J. Weeks, Libero Ajello, Robert H. Hutcheson, Stanley L. Wiener, Dwight W. Lambe, Tom A. Sayvetz, William Schaffner,
Tópico(s)Antifungal resistance and susceptibility
ResumoIn August 1980, an outbreak of acute pulmonary histoplasmosis occurred among participants in a wagon train as it traveled through eastern Tennessee. Of the 85 people on the train 69 (81 percent) had evidence of infection with Histoplasma capsulatum. Fifty-four people had symptomatic disease. The source of infection was traced to the site of a former winter blackbird roost in Charleston, Tennessee, that had been partially cleared five years earlier to make a park. Fourteen of 25 soil samples from this site were culture-positive for H. capsulatum. This is the first reported outbreak to involve a large migrant group. The outbreak is unusual in that exposure occurred without excavation, construction or tree-cutting at the site.
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