Portal de Periódicos da CAPES

Oral delivery of anticancer drugs III: formulation using drug delivery systems

2012; Elsevier BV; Volume: 18; Issue: 1-2 Linguagem: Inglês

10.1016/j.drudis.2012.08.007

1878-5832

Silvia Mazzaferro, Kawthar Bouchemal, Gilles Ponchel,

Drug Solubulity and Delivery Systems

In the past few years, the growth of nanometric size drug delivery systems (DDS) has burst into challenging innovations enabling real progresses to achieve oral delivery of anticancer drugs. DDS, such as polymeric nanoparticles, micelles, dendrimers and lipid-based formulations enable physico-chemical properties of cytotoxic agents to be improved and oral bioavailability to be enhanced. In this review we highlight current DDS used for the oral delivery of anticancer drugs.