Artigo Revisado por pares

Competitive nucleophilic aromatic substitution and palladium-catalyzed alkoxycarbonylation of (substituted chloroarene)Cr(CO)3 complexes

1994; Elsevier BV; Volume: 35; Issue: 28 Linguagem: Inglês

10.1016/s0040-4039(00)73302-8

ISSN

1873-3581

Autores

Jean‐François Carpentier, Eric Finet, Yves Castanet, Jacques Brocard, André Mortreux,

Tópico(s)

Asymmetric Hydrogenation and Catalysis

Resumo

The reaction of Cr(CO)3-complexed chloroarenes with HCO2CH3 and NaOCH3 in the presence of a catalytic amount of PdCl2(PPh3)2 gives esters in good yields provided that the arene is substituted by an electron-donating group, whereas the presence of an electron-withdrawing substituent on the aromatic ring leads to ethers via an ipso nucleophilic aromatic substitution.

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