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Hybrid Vibrio vulnificus

2005; Centers for Disease Control and Prevention; Volume: 11; Issue: 1 Linguagem: Inglês

10.3201/eid1101.040440

1080-6059

Naiel Bisharat, Dani Cohen, Rosalind M. Harding, Daniel Falush, Derrick W. Crook, Tim Peto, Martin Maiden,

Genomics and Phylogenetic Studies

Abstract The recent emergence of the human-pathogenic Vibrio vulnificus in Israel was investigated by using multilocus genotype data and modern molecular evolutionary analysis tools. We show that this pathogen is a hybrid organism that evolved by the hybridization of the genomes from 2 distinct and independent populations. These findings provide clear evidence of how hybridization between 2 existing and nonpathogenic forms has apparently led to the emergence of an epidemic infectious disease caused by this pathogenic variant. This novel observation shows yet another way in which epidemic organisms arise.