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Current therapy for cutaneous melanoma

1995; Elsevier BV; Volume: 32; Issue: 5 Linguagem: Inglês

10.1016/0190-9622(95)91443-9

1097-6787

Timothy M. Johnson, John W. Smith, Bruce R. Nelson, Alfred E. Chang,

CAR-T cell therapy research

We review the current therapy for melanoma. The diagnosis, prognostic variables, staging, treatment, and follow-up guidelines for cutaneous melanoma are reviewed from the earliest to the most advanced stages. New guidelines for margins are discussed. A new, evolving, innovative radiographic technique, positron emission tomography using 2-fluorine-18-fluoro-2-deoxy-d-glucose, may be useful to identify subclinical nodal and visceral disease. Recent advances with respect to tumor vaccines, gene therapy, immunotherapy, and interleukin 2 as well as current concepts regarding lymph node dissection are discussed.