Synthesis of Novel Amphiphilic and pH-Sensitive ABC Miktoarm Star Terpolymers
2006; American Chemical Society; Volume: 39; Issue: 17 Linguagem: Inglês
10.1021/ma0606859
ISSN1520-5835
AutoresKathy Van Butsele, François Stoffelbach, R. Jérôme, Christine Jérôme,
Tópico(s)Dendrimers and Hyperbranched Polymers
ResumoNovel amphiphilic ABC miktoarm star terpolymers were synthesized that consist of hydrophilic poly(ethylene oxide) (PEO), hydrophobic poly(ε-caprolactone) (PCL), and pH-sensitive poly(2-vinylpyridine) (P2VP), thus a water-soluble block upon protonation. In the first step, poly(ethylene oxide monomethyl ether) (MPEO) was capped by one ω-epoxy end group by reaction of the original hydroxy end group with epichlorohydrin. MPEO-b-P2VP diblock copolymers were prepared by nucleophilic addition of living P2VP-Li+ chains onto the epoxy group of MPEO's. Finally, the hydroxy group formed at the junction of the MPEO and P2VP blocks was used to initiate the ring-opening polymerization of ε-caprolactone in the presence of tin octoate. The ABC star-shaped triblocks were characterized by 1H NMR spectroscopy and size exclusion chromatography.
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