Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository
2009; Elsevier BV; Volume: 75; Issue: 2 Linguagem: Inglês
10.1016/j.urology.2009.05.050
ISSN1527-9995
AutoresLisa F. Newcomb, James D. Brooks, Peter R. Carroll, Ziding Feng, Martin Gleave, Peter S. Nelson, Ian M. Thompson, Daniel W. Lin,
Tópico(s)Bladder and Urothelial Cancer Treatments
ResumoActive surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. Outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. However, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveillance from the indolent cancers. The Canary Prostate Active Surveillance Study is a multicenter study and a biorepository that will discover and confirm biomarkers of aggressive disease as defined by histologic, prostate-specific antigen, or clinical criteria.
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