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European Ancestry as a Risk Factor for Atrial Fibrillation in African Americans

2010; Lippincott Williams & Wilkins; Volume: 122; Issue: 20 Linguagem: Inglês

10.1161/circulationaha.110.958306

1524-4539

Gregory M. Marcus, Álvaro Alonso, Carmen Peralta, Guillaume Lettre, Eric Vittinghoff, Steven A. Lubitz, Ervin R. Fox, Yamini S. Levitzky, Reena Mehra, Kathleen F. Kerr, Rajat Deo, Nona Sotoodehnia, Meggie Akylbekova, Patrick T. Ellinor, Dina N. Paltoo, Elsayed Z. Soliman, Emelia J. Benjamin, Susan R. Heckbert,

Diabetes, Cardiovascular Risks, and Lipoproteins

Despite a higher burden of standard atrial fibrillation (AF) risk factors, African Americans have a lower risk of AF than whites. It is unknown whether the higher risk is due to genetic or environmental factors. Because African Americans have varying degrees of European ancestry, we sought to test the hypothesis that European ancestry is an independent risk factor for AF.