Portal de Periódicos da CAPES

Burkitt's lymphoma in the middle east a study of 34 cases

1985; Wiley; Volume: 56; Issue: 10 Linguagem: Inglês

10.1002/1097-0142(19851115)56

1097-0142

Elias Anaissie, Sima Geha, Charles Allam, Joseph E. Jabbour, Maryse Khalyl, Philip A. Salem,

CNS Lymphoma Diagnosis and Treatment

CancerVolume 56, Issue 10 p. 2539-2543 ArticleFree Access Burkitt's lymphoma in the middle east a study of 34 cases Elias Anaissie MD, Elias Anaissie MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorSima Geha MD, Sima Geha MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorCharles Allam MD, Charles Allam MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorJoseph Jabbour MD, Joseph Jabbour MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorMaryse Khalyl, Maryse Khalyl American University Medical Center, Beirut, LebanonSearch for more papers by this authorPhilip Salem MD, Corresponding Author Philip Salem MD American University Medical Center, Beirut, LebanonAmerican University Medical Center, PO Box 113-6044, Beirut, Lebanon===Search for more papers by this author Elias Anaissie MD, Elias Anaissie MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorSima Geha MD, Sima Geha MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorCharles Allam MD, Charles Allam MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorJoseph Jabbour MD, Joseph Jabbour MD American University Medical Center, Beirut, LebanonSearch for more papers by this authorMaryse Khalyl, Maryse Khalyl American University Medical Center, Beirut, LebanonSearch for more papers by this authorPhilip Salem MD, Corresponding Author Philip Salem MD American University Medical Center, Beirut, LebanonAmerican University Medical Center, PO Box 113-6044, Beirut, Lebanon===Search for more papers by this author First published: 15 November 1985 https://doi.org/10.1002/1097-0142(19851115)56:10 3.0.CO;2-5Citations: 26AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract The clinical features of 34 patients with Burkitt's lymphoma diagnosed at the American University Medical Center (AUMC) are described. Ages ranged between 3 and 20 years (median, 7 years). Seventy-three percent of the patients were younger than 8 years. Three cases occurred among siblings. The primary site of disease at presentation was the abdomen, 23 patients; jaw, 6; jaw and abdomen, 2; Waldeyer's ring, 2; and mediastinum, 1. Of those who had abdominal disease, the involvement was diffuse and extensive in abdomen and pelvis in 9, apparently confined to the ileocecal region in 5, mesenteric nodes and small intestine in 5, large intestine in 1, and ovary in 3. One patient presented with paraplegia. The bone marrow was studied in 19 patients; it was positive in 5 and suspicious in 2. None had frank leukemia. CSF was studied in 4 patients at presentation and was negative. Eight patients developed meningeal lymphoma during the course of the disease. Liver involvement was documented in 3 patients. Peripheral lymphadenopathy was observed at presentation in 11 patients (9, neck; 2, inguinal + axillary). In contrast to African Burkitt's, the majority of our patients presented with abdominal disease, and in contrast to the American form, our patients were younger with a median age similar to that of African Burkitt's. Thirty percent of the patients had jaw tumor at presentation—a figure intermediate between the African and the American Burkitt's. Citing Literature Volume56, Issue1015 November 1985Pages 2539-2543 ReferencesRelatedInformation