Solid-phase combinatorial synthesis and cytotoxicity of 3-aryl-2,4-quinazolindiones
2002; Elsevier BV; Volume: 10; Issue: 3 Linguagem: Inglês
10.1016/s0968-0896(01)00299-1
ISSN1464-3391
AutoresHea-Young Park Choo, Mi‐Hyun Kim, Sang Kook Lee, Sang Woong Kim, In Kwon Chung,
Tópico(s)Synthesis and biological activity
ResumoA series of 3-aryl-2,4-quinazolinediones with various substitution on aromatic rings has been prepared by solid-phase synthesis. Several compounds showed cytotoxicity on human colon carcinoma (Col2) tested by SRB method.
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