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Spirostanol and Furostanol Glycosides from the Fresh Tubers of Polianthes tuberosa

2003; American Chemical Society; Volume: 67; Issue: 1 Linguagem: Inglês

10.1021/np034028a

1520-6025

Jian‐Ming Jin, Ying‐Jun Zhang, Chong‐Ren Yang,

Natural product bioactivities and synthesis

Six new steroid glycosides--two spirostanols, polianthosides B and C (1, 2), and four furostanols, polianthosides D-G (3-6)--were isolated from the fresh tubers of Polianthes tuberosa, together with seven known spirostanols (7-13) and a known furostanol (14) saponins. Their structures were elucidated on the basis of spectroscopic analysis and the results of acidic and enzymatic hydrolysis. The cytotoxic activities of 1-14 against HeLa cells are reported.