Portal de Periódicos da CAPES

The Association Between Lower Urinary Tract Symptoms and Renal Function in Men: A Cross-Sectional and 5-Year Longitudinal Analysis

2006; Lippincott Williams & Wilkins; Volume: 175; Issue: 4 Linguagem: Inglês

10.1016/s0022-5347(05)00641-5

1527-3792

Anton Ponholzer, Christian Temml, Rudolf P. Obermayr, Michael Rauchenwald, Stephan Madersbacher,

Urinary Tract Infections Management

We assessed the association between LUTS and renal function in men in a cross-sectional and a longitudinal study.Men participating in health investigation in Vienna entered this study. In the cross-sectional analysis a consecutive series of men were studied and in the longitudinal analysis men were reevaluated after 5 years. LUTS were assessed by I-PSS and renal function was evaluated by GFR, as calculated by the Cockcroft-Gault equation.A total of 2.469 men with a mean age of 47.1 years (range 30 to 80) entered the cross-sectional study and 439 with a mean age of 51.7 years (range 45 to 79) could be assessed in longitudinal analysis. In the cross-sectional study there was no association between the degree of LUTS and GFR during 5 life decades (p = 0.55). An identical pattern was observed for irritative and obstructive scores. In the longitudinal cohort mean GFR +/- SD decreased from 84.3 +/- 20.2 ml per minute at baseline to 79.2 +/- 18.7 ml per minute after 5 years (-6.0%, p 0.05). The only determinants for GFR less than 90 ml per minute were age (p <0.0001) and hypertension (p <0.0001).LUTS do not represent an independent risk factor for impaired renal function in men.