Artigo Revisado por pares

Application of isothermal microcalorimetry in solid state drug development

2000; Elsevier BV; Volume: 3; Issue: 1 Linguagem: Inglês

10.1016/s1461-5347(99)00227-8

ISSN

1879-0186

Autores

Mark A. Phipps, Lesley A. Mackin,

Tópico(s)

Analytical Chemistry and Chromatography

Resumo

Microcalorimetry is an analytical technique that has found numerous applications within the pharmaceutical environment. In the realm of pharmaceutics, especially solid state pharmaceutics, the technique has proved to be an invaluable tool. This review addresses the solid state applications of microcalorimetry within the pharmaceutical industry, with a specific focus on stability, compatibility and amorphicity determinations.

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