The Study of Congenital Anomalies by the Epidemiologic Method
1950; Massachusetts Medical Society; Volume: 243; Issue: 3 Linguagem: Inglês
10.1056/nejm195007202430301
ISSN1533-4406
Autores Tópico(s)Demographic Trends and Gender Preferences
ResumoIN ANCIENT times the birth of a deformed baby was commonly believed to be an omen, a supernatural judgment or the work of the devil. These attitudes were gradually discarded, and with an increased understanding and application of mendelian laws, anomalies present at birth were commonly interpreted as manifestations of genetically defective germ plasm. A succession of events during the past ten years, initiated by Gregg's observations1 in 1941 on the role of rubella as a cause of congenital cataract,2 has brought appreciation of the fact that congenital anomalies may be acquired as well as inherited. At about the same . . .
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