Selection of alcohols through Plackett‐Burman design in lipase‐catalyzed synthesis of anthranilic acid esters
2001; Wiley; Volume: 78; Issue: 1 Linguagem: Inglês
10.1007/s11746-001-0218-y
ISSN1558-9331
AutoresC. V. Suresh Babu, S. Divakar,
Tópico(s)Microbial Metabolic Engineering and Bioproduction
ResumoAbstract Lipase‐catalyzed synthesis of esters of anthranilic acid was attempted by employing alcohols of carbon chainlength C 1 –C 18 using Plackett‐Burman experimental design. Of the alcohols employed, methanol, decanol, cetyl alcohol, and stearyl alcohols showed 99.9% significance. Esterification of anthranilic acid with methanol gave the highest yield at 45.6%. This study allows the selection of better alcohols for esterification of anthranilic acid.
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