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Release of endogenous GABA from the cat red nucleus slices

1983; Elsevier BV; Volume: 270; Issue: 1 Linguagem: Inglês

10.1016/0006-8993(83)90814-4

1872-6240

Michinori Kubota, Hironobu Sakaguchi, Nakaakira Tsukahara,

GABA and Rice Research

The release of endogenous gamma-aminobutyric acid (GABA) from the cat red nucleus was studied in a slice preparation. Potassium-induced depolarization caused a release of GABA in a calcium-dependent manner. The release of GABA was also induced by veratrine and blocked by tetrodotoxin. The demonstration of release satisfies one of the important criteria for identification of GABA as the inhibitory neurotransmitter.