Stereocontrolled construction of a spiro fused bicyclo[2.2.2]Octane ring system by the intramolecular double michael reaction
1984; Elsevier BV; Volume: 25; Issue: 20 Linguagem: Inglês
10.1016/s0040-4039(01)81189-8
ISSN1873-3581
AutoresMasataka Ihara, Masahiro Toyota, Keiichiro Fukumoto, Tetsuji Kametani,
Tópico(s)Cancer Treatment and Pharmacology
ResumoThe lithium enolate from the cyclohexenone (8) possessing the α, β-unsaturated ester moiety caused an intramolecular double Michael reaction to produce stereoselectively the spiro fused bicyclo[2.2.2]-octane (10).
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