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Release characteristics of ibuprofen from excipient-loaded alginate gel beads

1995; Elsevier BV; Volume: 116; Issue: 1 Linguagem: Inglês

10.1016/0378-5173(94)00281-9

1873-3476

Sung‐Joo Hwang, Gye Ju Rhee, Ki Myung Lee, Kyoung Hee Oh, Chong Kook Kim,

Hydrogels: synthesis, properties, applications

Ibuprofen-loaded alginate beads were prepared and found to optimize in vitro release with zero-order kinetics. The release of ibuprofen could be controlled by adding excipients or by adjusting the NaAlg/ibuprofen ratio.