Rapid concentration and analysis of short chain carboxylic acids: variation on a theme
1982; Elsevier BV; Volume: 234; Issue: 1 Linguagem: Inglês
10.1016/s0021-9673(00)81798-7
ISSN1873-3778
Autores Tópico(s)Mass Spectrometry Techniques and Applications
ResumoPentafluorobenzyl (PFB) derivatives of chlorinated acetic and propionic acids were prepared adapting previously published methods to prepare PFB derivatives of non-chlorinated acids. Reaction of monochloro- and dichloroacetic acids and 2-chloro-, 2,2-dichloro- and 2,3-dichloropropionic acids with pentafluorobenzyl bromine (PFBBr) produced the PFB esters. Trichloroacetic acid reacted with PFBBr to give 1,1,1-trichloro-2-pentafluorophenylethane. On standing, this was partly degraded to 1,1-dichloro-2-pentafluorophenylethene. Gas chromatography-mass spectrometry, 1H NMR and 13C NMR were used to determine the structures of the derivatives.
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