Synthesis of substituted bis(heteroaryl)maleimides
2005; Elsevier BV; Volume: 61; Issue: 19 Linguagem: Inglês
10.1016/j.tet.2005.03.016
ISSN1464-5416
AutoresMathieu Dubernet, Virginie Caubert, Jérôme Guillard, Marie‐Claude Viaud‐Massuard,
Tópico(s)Synthesis of heterocyclic compounds
ResumoSubstituted bis(fur-2-yl), bis(fur-3-yl) and bis(thien-2-yl) maleimides with potential antidiabetic properties are described. Their synthesis involves, as a key step, a Suzuki cross-coupling between various boron derivatives and the diiodomaleimides. Therefore, a wide range of substituted symmetric and non-symmetric maleimide derivatives can be prepared.
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