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Survival of children with thyroid cancer in Europe 1978–1989

2001; Elsevier BV; Volume: 37; Issue: 6 Linguagem: Inglês

10.1016/s0959-8049(01)00010-7

1879-0852

Hans H. Storm, I Pleško,

Renal and related cancers

Thyroid cancers are rare in childhood with between 0.4 and 1.5 cases per million, 2–3 times as frequent in girls as in boys. However, following the Chernobyl accident, a remarkable incidence increase was observed in children exposed to radioactive iodine fall-out. Survival after thyroid cancer in childhood is thus of interest. In the EUROCARE II study, excluding most of Eastern Europe, a total of 165 childhood thyroid cancers were reported during the period 1978–1989, of which 134 were aged 10–14 years. The childhood cancer registry in England and Wales contributed 39% of the cases, and another 24% came from the Nordic countries, the rest from other parts of west, south, east and central Europe. The 5-year survival was for both genders combined 97% (95% confidence interval (CI): 93–99), 98% (95% CI: 91–100) for boys and 97% (95% CI: 91–99) for girls, with no significant difference between the genders. Survival was high during the entire study period, and variations influenced by the small numbers. As for adults, long-term follow-up beyond 10–20 years is needed to clearly demonstrate excess mortality as a consequence of the cancer.